Word: beckwithã
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...next step of the HMS researchers’ work will require collaboration between the discoveries made in Beckwith??€™s and Rapoport’s labs. The identification and understanding of the VKOR structure will help the researchers in their search for new tuberculosis antibiotics, Rapoport said...
...Beckwith??€™s team worked off of discoveries made in Rapoport’s lab, including the structure and function of the VKOR protein, its formation of disulfide bridges, and its method of inhibiting the VKOR enzyme...
...Beckwith??€™s team is currently developing screening assays for various anticoagulants and antibiotics to test whether they inhibit VKOR’s enzymatic activity. Dutton said they hope to “find other small molecules that would be stronger inhibitors that could potentially serve as starting points for new TB antibiotics...
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