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Adventureland, writer/director Greg Mottola's semiautobiographical ode to the languorous time just before adulthood responsibilities begin, makes you want to ditch your career (if it hasn't already ditched you), don some mildly humiliating uniform and return to the mundane summer job of your youth. Who can argue against cash flow, solidarity with a new peer group and no responsibility more strenuous than remembering who ordered the Sanka...
...support since Dec. 19, when the outgoing Bush Administration threw it a short-term loan and told the company that it had until March 31 to come up with a plan for its long-term survival. It did - but its strategy was premised on projections that car sales would begin to pick up this year after last year's dismal industry performance, in which sales sank 18%, to 13.2 million units. But the pickup hasn't happened yet, and analysts see the industry's production "run rate" at or below 9 million units. (Read about Detroit's efforts to reinvent...
...flies but also in higher-order mammals - may perform such a pressure-releasing role. During sleep, researchers theorize, the brain actively prunes the neural network laid out during waking hours, trimming away weaker connections that haven't been used in a while or weren't strong enough to begin with. The stronger connections are believed to be filed during sleep into long-term memory, where they can be accessed again and again as needed. All this nocturnal tidying creates room for new connections to be formed when the brain wakes again. "If this didn't happen, theoretically, over time...
...gold standard of medical evidence, the randomized controlled trial. And as convincing and as large as the current study is, Fauci notes that it too lacks this scientific imprimatur. In Kitahata's study, researchers followed patients as they and their doctors made their own decisions about when they would begin drug therapy. Those who chose to start early - before their CD4 counts reached 350 cells or 500 cells, for instance - may have simply been more health-conscious overall and therefore less likely to die, which could have confounded the study's results. Only a randomized and controlled trial in which...
...Still, Fauci acknowledges that the sheer size of Kitahata's study gives its findings some weight. She presented the preliminary data to a government panel on HIV-treatment guidelines in February, and the results have since gotten HIV experts talking about whether waiting to begin treatment until the current threshold of 350 cells is reached is too late to improve HIV patients' survival...