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Armed with a new biochemical understanding of how myxopyronin functions, along with detailed models of its behavior inside bacterial cells, researchers say drug development is feasible at last. Ebright says the drug could be in clinical human trials within five years. "What has not been possible previously was design of new derivatives ," says Ebright. "It's now possible to make new derivatives that are expressly designed to...have higher potency...

Author: /time Magazine | Title: A New Class of Antibiotics Could Offer Hope Against TB | 10/17/2008 | See Source »

Gage: The question of temperament can come to stand in for when there just don't seem to be a lot of other ways to predict someone's behavior ... and you've seen this much more in campaigns. George W. Bush is a good example. [He appeared] to be just very flat during the campaign. It was hard to tell what he thought ideologically. And how he behaved in office, of course, was different in those terms ... I was just trying to think of examples of moments that have become kind of our iconic moments of ideal presidential temperament...

Author: /time Magazine | Title: What Kind of Temperament Is Best? | 10/16/2008 | See Source »

Another Congressman, weeks from an election, is accused of untoward sexual behavior, contradicting his public stance as a moral crusader. He initially says as little as possible, offers opaque denials, vague apologies to his family for whatever he did or did not do, and predicts vindication...

Author: /time Magazine | Title: Mahoney's Florida District Has Sex-Scandal Déjà Vu | 10/16/2008 | See Source »

...reimbursed by Washington for disaster-recovery expenses, and that Martin County had been seeking funding prior to Mahoney's election.) Republicans have also accused leading Democrats of covering up whatever knowledge they had of Mahoney's trysts, the very same charge that was leveled at Republicans after Foley's behavior surfaced two years...

Author: /time Magazine | Title: Mahoney's Florida District Has Sex-Scandal Déjà Vu | 10/16/2008 | See Source »

...test this herd behavior, Berns and his colleagues hooked 32 people up to brain-imaging equipment and watched them reckon with a group opinion (about whether two shapes were the same or different) that was clearly false. They found that the brain worked to integrate the false opinion into its perception of the world. In other words, if other people start selling a stock you thought was valuable, you may want to do the same - at first...

Author: /time Magazine | Title: Fear Factor: This Is Your Brain in an Economic Crisis | 10/15/2008 | See Source »

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