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...August, a team of scientists at Northwestern University were the first to show why the brain's "memory function" fails in the face of an insulin shortage. The group's prior research had already pinpointed the culprit: toxic proteins called amyloid beta-derived diffusible ligands (ADDLs, for short), which are known to pile up in the brains of people with Alzheimer's. Scientists also knew that Alzheimer's patients' brains have lower levels of insulin and are insulin resistant. But what the Northwestern team discovered is the molecular mechanism behind that resistance: when ADDLs bind to neurons at synapses, they...

Author: /time Magazine | Title: Is Alzheimer's a Form of Diabetes? | 10/18/2007 | See Source »

Hanzich distinguished himself in the classroom as well, graduating as a member of the Phi Beta Kappa Honor Society and receiving a prestigious scholarship to the University of Cambridge to earn a master’s degree in public health over the past year...

Author: By Aditi Balakrishna, CRIMSON STAFF WRITER | Title: Memorial Service Honors Deceased Alum | 10/5/2007 | See Source »

...Hanzich, a native of Orange County, Calif., earned a slew of academic honors at Harvard while studying government, and served as a leader of several campus groups. He graduated as a member of the Phi Beta Kappa honor society and attended the University of Cambridge on a prestigious scholarship to earn a master’s degree in public health. He was a finalist for the Rhodes scholarship...

Author: By Aditi Balakrishna, CRIMSON STAFF WRITER | Title: Hanzich ’06 Leaves a Legacy of Leadership | 9/17/2007 | See Source »

...Harvard, Hanzich, a resident of Leverett House, was a member of Phi Beta Kappa honor society, a John Harvard Scholar, a Detur Book Prize winner, and a finalist for the Rhodes scholarship...

Author: By Aditi Balakrishna, CRIMSON STAFF WRITER | Title: '06 Grad Found Dead in New Haven | 9/16/2007 | See Source »

...deep end of science is where Jose Varghese likes to be. Part of the pioneering team that in the mid '90s developed the anti-influenza drug Relenza - one of only two drugs known to be effective against avian flu - Varghese is now focusing on an enigmatic protein, amyloid beta, and what he suspects are its toxic effects on the brains of people with Alzheimer's. In the international race to uncover amyloid beta's molecular structure - the crucial first step in finding out how to block its pathological effects - synchrotron X rays are a crucial tool. The molecules...

Author: /time Magazine | Title: Shedding Light on Matter | 8/24/2007 | See Source »

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