Word: betas
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Dates: during 1990-1999
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...turn to Al Gore '69, Mr. Beta-man-soon-to-be-alpha-man. Americans must be making the poor vice president so confused. On one hand, he's breaking all ties with the "Big Daddy" Bill Clinton administration. And if he takes away just one thing from Clinton's cigar antics, it's that leaders who can't seem to nail that family-values persona can and will be slammed...
...personality stretches beyond politics. Why the need to get so personal? Why the need to take it so personally? But I guess when your main rival comes in the form of a six-foot, five-inch ex-basketball star, it's enough to motivate any candidate to shed his beta-man skin...
...That may be because she's indispensable--or perhaps it's just her deep cover. Not even newly appointed campaign manager Donna Brazile knew of Wolf's involvement until recently. In the leaner operation that Brazile is running out of Nashville, Tenn., everyone has to sacrifice. Brazile, no Beta herself, cut Wolf's pay to $5,000 a month...
...target is a rogue protein known as beta amyloid, which forms the plaques that fill the brain's memory centers; just two weeks ago scientists identified one of the enzymes that are key to its formation. Another is an abnormal variant of the tau protein, which is thought to clutter the interiors of nerve cells with threadlike tangles. Over the coming years, as a new generation of Alzheimer's drugs enters the clinical pipeline, the arguments that rage today over which is more important, beta amyloid or tau, may be resolved. Kosik suspects that both may be critical...
...lessen the severity of symptoms. But by 2025, control could come to resemble a cure. For Alzheimer's has something in common with other brain disorders such as Parkinson's, Huntington's and mad-cow disease. Like them, it appears to be caused by misfolded proteins--in this case, beta amyloid and tau. And so one day in the 21st century it may become possible to vanquish Alzheimer's with a vaccine that targets these miscreants, or a new class of drugs that prevents them from forming. Kosik even has a name for these drugs--"broad-spectrum anti-aggregates...