Word: binding
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Cancer-causing mutations can occur quite by accident. But chronic exposure to carcinogens -- chemicals whose by-products bind to DNA and damage it -- greatly accelerate the rate at which dividing cells make errors. Proven carcinogens include asbestos, benzene and some ingredients of cigarette smoke. Many carcinogens, it turns out, are not blunderbusses but leave highly individualized fingerprints in the DNA they touch. At the National Cancer Institute, Dr. Curtis Harris, a molecular epidemiologist, has been examining cells from liver- and lung-cancer patients, searching for mutations in a tumor-suppressor gene known as p53 (p stands for the protein...
This time, though, the strategy is not working quite so well. Clinton did draw sympathetic responses from the crowds he worked; at a "town meeting" in Nashua, a woman remarked that she thought Whitewater was for rafting and canoeing. But back in Washington the Administration was in a worsening bind, facing congressional hearings about Whitewater and the near-certainty of further revelations and unable to stop either. Special prosecutor Robert Fiske subpoenaed a 10th Administration official, senior adviser George Stephanopoulos, possibly to ask him what he may have said about Whitewater in phone conversations with Deputy Treasury Secretary Roger Altman...
...collecting. The punishment for late study cards is not unlike old-time punishments for defaulting on debt. Like the debtor, who was shipped off to debtor's prison and rendered even less capable of paying off whatever debts he had incurred, the study card slacker, most likely in a bind because he was unable to get a necessary signature, finds the number of signatures he needs to get hopelessly multiplied. Fines and signatures mount until the hapless victim must deliver up to the Registrar the riches of Croesus and an autograph book worthy of...well, someone with a really...
...when it comes to playing politics with the Megaplex, it's easy to fumble. Flaherty, in fact, has gotten himself into a mega-political bind over the issue. Flaherty authored the Megaplex legislation, but now has emerged as one of the most vocal opponents of his own bill...
...will put off sending the proposals to Congress until his health-care legislation has moved through committee -- the same committees that would handle welfare reform. That could be six to 10 months from now. To do otherwise, argues one high Administration official, could put potential allies in a bind. "If some members of Congress feel they would be tugged to the left in health-care reform, they might want to go to the right in welfare reform, to the detriment of our program...