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...help individualize treatment for breast cancer patients and provide additional options for those patients resistant to drugs currently used for treatment, according to the senior author, Harvard Medical School (HMS) Associate Professor of Medicine Myles A. Brown. Estrogen contributes to tumor cell growth via its role in binding to a protein net known as the estrogen receptor (ER), located in the nucleus of 70 percent of breast cancer cells. When estrogen attaches to this receptor, the binding initiates a flurry of activity in genes directly related to cell growth and division. Many cancerous cells have a disproportionately high number...

Author: By Aditi Balakrishna, CONTRIBUTING WRITER | Title: Genetic Map Adds to Cancer Research | 10/5/2006 | See Source »

...creative cultural epochs in history,” exploring “how works of literature and art function within a given society.” Which is excellent, because the courses have equally obtuse subject matter and syllabi. Students might question the ties that bind classes like C-20, “The Hero of Irish Myth and Saga” and C-51, “Revolution and Reaction: The Rise and Fall of the Russian Avant-Garde.” A common theme seems to be the study of how a specific kind of art worked...

Author: NO WRITER ATTRIBUTED | Title: Lit and Arts C | 9/14/2006 | See Source »

...understandable that Little League officials find themselves in a bind. Even before the new limits go into effect, there are plenty of parents and coaches who think the organization is not competitive enough and are choosing to participate in one or more travel teams that often don't restrict pitching. There's no guarantee that anyone will follow Little League's lead in counting pitches. Then the question becomes, Which will your child have longer--a nice, shiny trophy from winning a tournament or the injury he or she sustained getting it? ELBOW...

Author: /time Magazine | Title: How We're Harming Young Athletes | 9/10/2006 | See Source »

...deftly juggled snakes as they sought to plunge their venomous fangs into his arm or face, all the while keeping up a lively commentary for the cameras of his multimillion-dollar documentary operation. Scratched, bitten and bruised, he would display his wounds like trophies, casually using gaffer tape to bind up a severe bite from a large saltwater crocodile that he had been wrestling in a mangrove swamp. And the Crocodile Hunter understood how his risk-taking made him a cult hero to millions in the 130 countries where his films aired: his fans aped his trademark cry of "Crikey...

Author: /time Magazine | Title: Death of a Crocodile Hunter | 9/7/2006 | See Source »

...deftly juggled snakes as they sought to plunge their venomous fangs into his arm or face, all the while keeping up a lively commentary for the cameras of his multimillion-dollar documentary operation. Scratched, bitten and bruised, he would display his wounds like trophies, casually using gaffer tape to bind up a severe bite from a large saltwater crocodile that he had been wrestling in a mangrove swamp. And the Crocodile Hunter understood how his risk-taking made him a cult hero to millions in the 130 countries where his films aired: his fans aped his trademark cry of "Crikey...

Author: /time Magazine | Title: Death of a Crocodile Hunter | 9/4/2006 | See Source »

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