Word: bindingly
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...them to choose candidates and fund them (hopefully under new, stricter campaign finance laws), or whether we want to continue in the current descent towards candidate-driven elections where personality means more than policy and political extremists set the primary agenda (think Bob Jones University). Without a party to bind candidates to specific policies, clear goals and a coherent vision, candidates freewheel through campaigns on their smile, their handshake and their looks, catering to the extremists on either side before rushing to the middle--never mind the hypocrisy inherent in that...
...This political stalemate has left Nicholas Callaway, founder of the book?s publisher, Callaway Editions, in a bit of a bind. "At this point, only those first 8,000 copies will be shipped from our warehouse to bookstores," he told TIME.com. "We?ve been forced to ration the books, because the existing copies won?t meet the demand or fill our advance orders." The publishing house, which, like many of its competitors, has worked with Chinese manufacturers for ten years without incident, had planned a major fall lineup to mark its entr?e into the world of full-service publishing. Unfortunately...
Poetic justice, perhaps, that the home of reality fare like Alien Autopsy should end up in this semantic bind. Yet you can forgive American High (Wednesdays, 9 p.m. E.T.) the creative phrasing: What is high school if not Survivor with diplomas? Besides, this reality series/teen show is a thousand times realer, factually and emotionally, than Big Brother and Dawson's Creek put together. That's partly because Cutler, who produced The War Room and directed A Perfect Candidate, let the kids film their own "video diaries" and partly because the show's MTV-meets-PBS kineticism captures the confused rush...
...Spider venom is a gold mine of pharmacological tools," explains Michael Adams, a venom-using neuroscientist at the University of California at Riverside. The active compounds in venom bind with extreme selectivity to molecules on the surfaces of living cells, a property that can be of invaluable use to researchers developing new medicines with better specificity (and thus fewer side effects) or just trying to understand, at the molecular level, the inner workings of living cells...
...Gordon, an expert on treating high cholesterol, became intrigued with the fact that cholesterol and blood lipids (fats) in people with severe illness or injury tend to drop to abnormally low levels. This makes them more vulnerable to sepsis, he reasoned, because one of the lipids' functions is to bind to and neutralize endotoxins. His unorthodox solution (especially for someone known for fighting high cholesterol): try to raise lipid levels in sepsis victims...