Word: bindings
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...bind from which she has been unable to extricate herself and one that is crippling her presidency. She has been "tentative in pursuing reforms," says one of her congressional opponents, Senator Rodolfo Biazon. Arroyo is fearful, he believes, of upsetting her already rankled ex-backers. One of those is Archbishop Jaime Cardinal Sin, the outspoken prelate who has wielded the church's immense moral authority to pummel Presidents into line for almost two decades. Earlier this month, Sin released an ominous statement declaring the state of politics was "far from ideal"; it didn't directly point the finger at MalacaNang...
...home. While Arafat unconvincingly condemned the smuggling incident and vowed to punish those responsible, the ship's captain may have been expressing the view of a majority of ordinary Palestinians when he said simply, "It is my people's right to defend themselves." But Arafat is caught in a bind, because even if he has his own doubts about the rewards of diplomacy, the response of the Americans and Europeans to the Karine A incident is an unambiguous reminder that the international peace brokers will not allow him to maintain armed struggle as a fall-back option while pursuing...
...those proteins, called a class I major histocompatibility complex (MHC) molecule, helps the body identify cells that have been infected with viruses. The molecule, which comes in several different variations, is able to bind to pieces of thousands of different types of viruses. The way the molecule binds and presents the pieces to the immune system was a mystery until Wiley’s work on the subject in the 1980s...
...costs and inefficiency of this approach are staggering. Today's drugs attack just 500 out of an estimated 5,000 proteins that they could be devised to attack. On average, only 1 in 1,000 molecules that bind to a target makes its way to human trials. Of the survivors, just 1 in 5 reaches the market. If failures are taken into account, pharmaceutical companies on average spend $802 million--and 10 to 15 years--to develop each new drug, according to a report released on Nov. 30 by the Tufts Center for the Study of Drug Development in Boston...
...announcement puts Arafat in a bind, not only because it makes it more difficult for him to arrest Hamas members, but also because of the distinction made between Israel-proper and the West Bank and Gaza. The Islamist organization has left the door open to continue attacks against Israeli soldiers and settlers in the West Bank and Gaza, a position endorsed by the grassroots militants of Arafat's own Fatah organization and one that would find few critics in Palestinian civil society where the settlements are viewed as an illegal and intolerable presence. But Israel and the U.S. are unlikely...