Word: binds
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Dates: during 2010-2019
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Stephen W. Fesik, professor of biochemistry, pharmocology, and chemistry at the Vanderbilt School of Medicine, presented audience members with a series of proteins that bind to other proteins and may serve as viable treatments for cancer patients in the future at yesterday’s 14th Andrew H. Weinberg Memorial Lecture at Harvard Medical School...
...structure-based drug design, the three-dimensional structure of the designated biological target determines the components of the treatment while fragment-based approaches in drug discovery employ physical techniques to determine how fragments bind to protein targets...
...Fragment-based screening involves highly-focused chemistry,” he said. “It tailors molecules to bind to a protein target of interest and covers more chemical space, while identifying hits not obtained in other screens...
...further, with a call to jettison the term special relationship as ruthlessly as colonists once dumped tea into Boston Harbor. The expression was coined by no less a person than Winston Churchill in 1946 to describe the intricate skeins of mutual interest, cultural heritage and sometimes gloopy sentiment that bind Washington and London. Globalization and "shifts in geopolitical power" mean that both countries are inevitably forming new and deep alliances with other players, and talk of a "special relationship" is increasingly misleading, says the report. "The overuse of the phrase by some politicians and many in the media serves simultaneously...
...reducing the child's exposure and by making sure he or she eats a balanced diet with sufficient iron, calcium and vitamin C - deficiencies in these can increase the body's absorption of lead. In extreme cases of extended lead exposure, doctors use drugs called chelating agents, which bind to the lead and pull it out of the body through urine. In severe cases of prolonged poisoning, however, the cognitive and developmental damage may be permanent, says Dr. Cristiane Lin, the study's lead author, who is now at Seton Medical Center in Austin, Texas. (See pictures of what...