Word: biotechs
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Mullen's vision didn't immediately play well with biotech investors, many of whom prefer the promise of blowout growth to steady profits. Shares of both companies dropped sharply. Who needs another giant drug company pumping out me-too pills, focusing on stuff it already makes and pinching pennies to deliver a steady income? Biotech's allure since the benchmark Genentech IPO 23 years ago has been its promise to deliver wonder drugs that will cure feared ailments like cancer and Alzheimer's. Yet with an exhaustingly long list of failed products and failed companies in its brief past...
...solidly profitable. Yet "the combination will create more value than either could as separate entities," says William Rastetter, CEO of IDEC, who would get the title of executive chairman after the merger. The focus on managing will probably spill down as more treatments reach the market and more biotech firms start writing in black ink. A wave of mergers could sweep the industry, though that might be several years away...
There are about three dozen biotech firms that regularly make money today. That number could triple by 2007, says Viren Mehta, principal at Mehta Partners, a global health-care investment group. Turning the corner on profits is more critical than ever, because large drug companies have tired of taking big risks in biotech and tend to shun early-stage research in favor of safer investments in drugs near approval or already approved. Bristol-Myers Squibb made a disastrous $2 billion investment in 2001 in ImClone Systems, which suffered costly setbacks with its cancer drug Erbitux before that drug...
...even if his deal goes through (Genentech is seen as a competing suitor for IDEC) and even if he manages to instill a new level of management intensity in the industry, biotech will remain a dicey game. Only one drug in 5,000 screened makes it to market, and even seasoned health-care investors are reluctant to handicap the process. "We'll take the risk that a company fails to execute its plan once it has a drug approval," says Stuart Weisbrod, chief investment officer of Merlin Biomed, a health-care hedge fund. "What we don't want...
...Biotech stocks soared in 1990-91 amid a flood of early-stage drug hype and IPOs. The vast majority of the drugs and companies soon failed, and the stocks crashed. Another bubble surfaced in 1999-2000. While everyone was focused on the run-up in Internet stocks, biotech shares rose twice as fast, largely driven by excitement over the mapping of the human genome. In the 18 months before March 2000, the American Stock Exchange's biotech index rose 563% while the NASDAQ rose 238%. Both plunged in the next two years...