Word: bismuthate
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Dates: during 1940-1949
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...Best drug for early syphilis is still old 606 (arsphenamine), combined with bismuth, though the simpler mapharsen may ultimately replace 606. In comparison, the time-honored mercury is not much good. The first three injections must be given within ten days; the rest once a week for several years. After the first injection a patient becomes temporarily noninfectious. But Dr. Moore warned doctors against the common practice of sporadic injections; once started, treatment must be continued, for in early syphilis a little "may be worse than none." Reason: if no drugs are given, the body proceeds with its strong defenses...
...treatment. On the second floor they fill out records telling a few facts about their customers. Then they are given a blood test. If infected, they are treated at once to make the diseases non-catching. For gonorrhea, they get sulfathiazole tablets; for syphilis, slow injections of neoarsphenamine and bismuth. Even if not infected, all of the 425 known prostitutes in town report to the clinic once a week...
...crisis stomach" worrying about bombing and gassing, about Mr. Chamberlain and what would happen after the war. But through it all ran a thin wire of pluck, which showed itself best in humor. Those were the days when a West End druggist put a placard in his window: "Bismuth as usual during altercations...
...bulk of chiropodic practice consists of corn trimming. Last week Podiatrists James S. Bowman and Robert E. Fowler of Temple University School reported a new way of removing corns by injection. They inject solutions of a bismuth compound or salt water or even sterile water around the margin of the corn, thus choking off the tiny blood vessels which feed it. After several injections, the corn dissolves. This treatment, they cautioned, is still in an experimental stage...
...preventive value of bismuth for syphilis was made clear in the 1920s by Dr. M. E. Sonnenberg of Poland, who gave bismuth injections to prostitutes for five years, obtained 95% protection. For the past ten years, fierce Dr. Paul John Hanzlik and his co-workers at Stanford University have been working to put bismuth into practical anti-syphilis pills. Recently they settled on a soluble sodium bismuthate compound which they called "sobisminol." Last week in the American Journal of Syphilis, Gonorrhea and Venereal Diseases they were able to publish an impressive summary of results...