Word: blakes
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Dates: during 1980-1989
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...believes will inevitably come after Mitterrand-as he foresees it-has crippled France's economy and its political institutions. "In my Loire Valley retreat," Giscard had mused bitterly in a pre-election allusion to his possible defeat, "I will be the most popular man in France." -By Patricia Blake. Reported by Henry Muller/Paris
...test, described by Medical Researchers David Blake and Stephen Spielberg, white blood cells from humans are mixed with liver tissue from humans or other species plus the drug under study. Then the preparation is examined to see if enzymes in the liver have metabolized the drug into a substance that kills white cells. The researchers believe that such toxic metabolites may be responsible for birth defects; some of their studies suggest that thalidomide works that way. The new test, for instance, shows that thalidomide does form a toxic metabolite, areneoxide, in the presence of liver tissue from rabbits, monkeys...
...Blake and Spielberg caution that this test will not alert investigators to all drugs with the potential for causing birth defects, only to those that form toxic metabolites. But they think their work could help researchers design more reliable experiments. For example, if a test shows that a .particular drug forms a toxic metabolite in humans and rabbits, but not, say, in dogs, then by a process of elimination rabbits would be designated the appropriate species for future birth defect studies related to that drug...
...exhibition offers that desire in all its facets. It shows itself to spectacular effect in the obsessed, lyrical mysticism of Runge, a painter who was perhaps the closest equivalent to William Blake that Germany ever produced. In Runge the world is imagined in extreme detail, near and far, as a sort of metaphysical machine, a generator of intricate meanings about the life of the universe: birth, death, renewal, metamorphosis. His ambition (never fulfilled) was to do a cycle of religious murals, Four Times of Day; they would be installed in a special chapel and would form, Runge hoped, the nucleus...
...Patricia Blake. Reported by Henry Muller/Paris