Word: bloch
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Four-Ring Cluster. The American is Harvard's Konrad Emil Bloch, 52, who came to biochemistry via chemical engineering. Early in his research Dr. Bloch learned that most of the cholesterol in the bodies of both animals and men comes not from cholesterol in food (though butterfat, egg yolks and meat fats contain much of it) but from built-in cholesterol factories. These factories are mainly in the liver, but many of the body's other cells can make some cholesterol. To discover how they do it, Dr. Bloch had to go back to the biochemical beginning...
...chemicals-including many fatty substances and most adrenal and sex hormones-having one thing in common: a four-ring cluster of carbon atoms, known as "the steroid nucleus." Other attached atoms give each steroid its distinctive character (see diagram). By growing rat-liver cells in the test tube, Dr. Bloch learned that they make cholesterol from the much simpler acetate ion (acetic acid minus a hydrogen ion). "My work since then," he says, "has been on the processes that the cell uses to manufacture the cholesterol molecule. This is a fantastically complex sequence of approximately 36 biochemical reactions." Bloch adds...
Born a German in Neisse (now in Poland), Bloch graduated from Munich's Technische Hochschule in 1934. Because he was a Jew, he was not allowed to continue his studies. He spent two years in Switzerland, came to the U.S. in 1936, got his Ph.D. at Columbia in 1939, was naturalized in 1944. After an eight-year stint at the University of Chicago, he became Harvard's Higgins professor of biochemistry...
President Pusey has also announced the elections as Senior Fellows of David Owen, Gurney Professor of History and Political Science, and Herbert Bloch, professor of Greek and Latin...
...Owen and Bloch join with seven other scholars who, along with President Pusey and Dean Ford, are the Senior Fellows. These men each year select about eight young men for the Junior Fellowships, which provide three years at the University free for research, creative work or study, with access to all the University's facilities...