Word: blood
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Dates: during 1980-1989
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Click. A little boy, hating his older brother, lies in wait behind their bedroom door and strikes him so hard with a water carafe that it breaks. A gush of blood mingles with shattered glass...
...genetic abnormality known as SCID (for severe combined immunodeficiency), these mice usually die at an early age, often of pneumocystis pneumonia, the disease that kills many AIDS patients. The researchers implanted some 300 of the defective mice with tissue taken from human fetal thymus, where certain immune and blood cells develop, and with blood-forming cells from fetal liver. The implanted tissues soon produced mature human T cells, specialized white blood cells that help provide immunity against disease. Mice that additionally received fetal lymph tissue -- needed for the functioning of some immune cells -- also developed mature human B cells...
...Jolla team also used SCID mice. By comparison, however, their approach was simple. Circulating white blood cells taken from human adults were injected into mice. Almost immediately, the mice began replicating the cells. Within three weeks they had human immune systems with nearly correct proportions of all the major types of white cells found in human blood. Moreover, when the researchers injected these mice with tetanus toxoid, most of the animals produced human antietanus antibodies, further proof that their new immune systems were functioning as though they were naturally human...
There was yet another unexpected consequence of the experiment. After being injected with human immune cells, many of the mice suddenly developed rapidly growing cancers, perhaps caused by a virus in the blood of some of the donors; mice injected with cells not exposed to this virus did not develop the tumors. The implications for cancer research could be enormous: the rapid growth -- in eight to 16 weeks -- would afford scientists a rare opportunity to track the emergence and spread of cancer. Said Mosier: "This is an extraordinary breakthrough. We may be able to dissect that tissue week by week...
Flight Engineer Benjamin Zimmermann, 48, told of accompanying Hammadi to inspect the aircraft's exterior while it was on the tarmac in Algiers a few hours later. "Hammadi pointed to the door and the blood((stains)) running from the sill," said Zimmermann. "He made gestures to the pistol and himself . . . indicating that he was proud of his gun and himself for causing this." Hammadi repeated his denials that he had killed Stethem...