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Word: blood (lookup in dictionary) (lookup stats)
Dates: during 1980-1989
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After months of controversy, the Food and Drug Administration last week ended its ambivalent attitude toward a genetically engineered drug that dissolves blood clots. FDA Commissioner Frank Young announced that the agency had approved the use of tissue plasminogen activator, or t-PA, as an emergency treatment for heart attacks. The drug activates an enzyme that destroys fibrin, the protein that binds clots together. Arterial clotting is thought to be a factor in most of the 1.5 million heart attacks suffered annually in the U.S., so t-PA could save thousands of lives. With an injection of the drug, said...

Author: /time Magazine | Title: Medicine: Go-Ahead for A Wonder Drug | 11/23/1987 | See Source »

Young established a second panel, which based its decision on two new studies showing that the heart's ability to pump blood increases after administration of t-PA. This indicates the drug can limit damage during a heart attack. However, says Harvard Cardiologist Eugene Braunwald, t-PA "has to be given within four to six hours after symptoms occur...

Author: /time Magazine | Title: Medicine: Go-Ahead for A Wonder Drug | 11/23/1987 | See Source »

...make the company vulnerable in a recession. But Lorenzo notes that Texas Air has $1.2 billion in cash. And, he says, Continental's low costs and fares would make the company more able than most competitors to weather an economic downturn. Says Lorenzo: "We're putting a lot of blood, sweat and tears into a company that has the attributes to be successful." Maybe so, but the fastest way to make customer confidence take off might be to turn a divided work force into one that is pulling together...

Author: /time Magazine | Title: Is This Any Way to Run an Airline? | 11/23/1987 | See Source »

...stuff through exercise and proper diet has become a standard health regimen. Last week, however, in a landmark paper in the New England Journal of Medicine, a group of Finnish scientists provided dramatic endorsement for a drug that drastically lowers the incidence of such disease, chiefly by raising the blood levels of a type of cholesterol...

Author: /time Magazine | Title: Medicine: The Battle of the Lipoproteins | 11/23/1987 | See Source »

...experiment was designed to show the differing effects of two distinct types of cholesterol: low-density lipoproteins, or LDLs, and a variant known as high-density lipoproteins, or HDLs. LDLs are the villains of cardiology: these complex molecules ferry cholesterol through the blood vessels, allowing life-threatening deposits to accumulate within artery walls. Each 1% decrease in LDL levels lowers the risk of heart disease 2%. The "good" HDLs work as garbage trucks, sopping up excess cholesterol and inhibiting arterial deposits. Basically, these two substances make up the total human blood- cholesterol level, an indicator that signals vulnerability to coronary...

Author: /time Magazine | Title: Medicine: The Battle of the Lipoproteins | 11/23/1987 | See Source »

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