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...science behind it goes back much further. In the 1950s, researchers developed a vaccine to block fatal overdoses of the heart drug digitalis. In the 1970s University of Chicago researchers prompted monkeys to develop antibodies to heroin by attaching molecules of the drug to a protein from cow's blood. It was this model on which Kosten, who became interested in solving addiction as a medical student at Cornell, based TA-CD. Using the cholera bacterium as a vector is a crucial tweak in design; it allows the cocaine vaccine to sidestep the potential viral syndrome associated with other vaccines...

Author: /time Magazine | Title: A Drug to End Drug Addiction | 1/9/2008 | See Source »

...become tense or have a physical reaction, like nausea or hyperventilation, to stressful situations. Even after accounting for other mood problems, like depression or anger, and for a whole host of physiological and demographic indicators - including age, body mass index, education, blood pressure, cholesterol levels and smoking and drinking habits - the effect of chronic anxiety was clear. It was also a stronger risk factor for heart attack than any of the other psychological problems in the study...

Author: /time Magazine | Title: A Link Between Anxiety and Heart Attacks | 1/8/2008 | See Source »

...first witness in the long-postponed trial of former Liberian President Charles Taylor wasn't invited to address the alleged atrocities that engendered war crimes charges, to which Taylor has pleaded innocent. Instead, he came to talk about "conflict" or "blood" diamonds. The heart of the prosecution's case is that Taylor terrorized the people of neighboring Sierra Leone in order to appropriate its diamond wealth for his own ends. Taylor is being tried on 11 counts in a special court in The Hague, including murder, rape, mutilation, and conscripting child soldiers in neighboring Sierra Leone...

Author: /time Magazine | Title: Charles Taylor Trial Starts | 1/7/2008 | See Source »

There aren't likely to be any honorable blockbusters this year. Instead, the nominees for the Best Picture Oscar are almost sure to include No Country for Old Men and There Will Be Blood, two ultraviolent dramas much loved by critics but too weird to be crowd pleasers. Atonement could fill the period-film slot; Sweeney Todd might get a nod for its crimson passion. With all this caviar on offer Oscar night (if there is an Oscar night), the beer-and-nachos audience will stay away, and the ratings will suffer VDD--viewer deficit disorder...

Author: /time Magazine | Title: How to Save the Awards Shows | 1/3/2008 | See Source »

...Huckabee said last night, in an appearance with Jay Leno on the Tonight Show, politics is a brutal business. "I tell people that if you can't stand the sight of your own blood, don't run for anything," Huckabee joked. "Just buy a ticket and watch it from the stands." Over 11 months of non-stop campaigning, Huckabee has come from nowhere to earn his place on the field. After Iowa, he'll get a better sense of how long he'll get to keep playing...

Author: /time Magazine | Title: Does Huckabee Have to Win Iowa? | 1/3/2008 | See Source »

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