Word: bloods
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...specifically altering genes in the progenitive bone cells of mice, the researchers were able to observe a profound disruption of blood formation...
...hematologist, [the disruption] reminded me of a disease seen in humans called myelodysplastic syndrome (MDS), which tends to evolve into the blood cancer leukemia,” Raaijmakers said...
This discovery demonstrates that instead of arising through mutations primarily in the blood cells, as previously thought, cancer may be formed in support cells—the bone marrow...
...research team will now have to investigate the exact signals that occur between the bone and blood cells in order to figure out which are pertinent to the formation of leukemia...
...already conducting follow-up research to continue and build upon this discovery. Because the model was conducted on mice, and thus has not yet been proven on humans, Scadden said the team of researchers is now “examining the cellular setting of patients with these human blood cancers...