Word: bloodstream
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Dates: during 1980-1989
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...bran works is still a mystery. One theory is that soluble fiber, which is plentiful in oats as well as citrus fruits and peas and beans, binds up cholesterol-rich bile acids that aid in digestion, thus helping to remove LDLs from the bloodstream. Health experts, however, are cautioning that many new oat products are high in saturated fats and calories. Kellogg's Cracklin' Oats cereal, for example, is made with coconut oil, a dietary no-no. And many muffins are loaded with eggs and sugar. Moreover, oat enthusiasts are mistaken if they think scarfing down oats allows them...
...that was it. But physicians are finding that the old-fashioned ways of delivering medication can render treatment hopelessly ineffective -- even dangerous. Some people just forget to take pills, and repeated trips to the doctor for shots can be unpleasant and expensive. Tablets and injections can flood the bloodstream with drugs and disperse them unevenly through the system. And drugs can have toxic side effects. With an array of potent, highly specialized new therapeutic drugs on the market, scientists are busy developing a dazzling assortment of space-age techniques that promise to deliver the drugs to the body in safe...
...Langer and his colleagues reconfigured the structure of polymers to enable drugs to be dispensed in measured doses. Explains Langer: "Because its route is so tortuous, the drug gets out, but slowly." Langer is now testing an injectable system for diabetics in which enzymes sensitive to glucose in the bloodstream are placed in microscopic polymers along with insulin. The drug is released through the complex, porous polymer structure. Because the solubility of insulin increases in the presence of glucose, the more glucose in the blood, the more drug is released. This "intelligent" method represents a potential revolution in the treatment...
...Mountain View, Calif., a biotechnology company is developing a nasal spray for diabetics that uses "enhancer molecules" to coat and carry insulin through the mucous membranes and into the bloodstream. Preliminary tests show that a wisp of the spray at mealtime may mimic the healthy body's response to rising blood-sugar levels. According to the company, the insulin can take full effect in less than 15 minutes, in contrast to two to three hours for an injection...
...Magic is the bloodstream of the universe," goes the refrain in Willow, but the blood is tired this time. The old legerdemain may save a kingdom, but it can't save this movie and, maybe, the fantasy genre. The man who soared on the zeitgeist can sink when it changes. George Lucas has worked his magic before and surely will again. But for now, the wonder wand is broken...