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...does the body digest and absorb triglycerides but not a sucrose polyester such as olestra? Both types of molecule, explains P&G chemist Ron Janacek, are too large to pass unaltered through the mucous membrane of the small intestine and into the bloodstream. With triglycerides, an intestinal enzyme known as lipase acts as a kind of molecular scissors, fitting into slots between the fatty acids and snipping them apart. But when there are too many fatty acids clumped too close together, as happens with olestra and other types of sucrose polyester, these slots are concealed and the enzyme cannot...

Author: /time Magazine | Title: HEALTH: ARE WE READY FOR FAT-FREE FAT? | 1/8/1996 | See Source »

...compendium of evil (war, suicide, poverty, injustice, exploitation) that yet asks us to believe that common decency (and a strong back) can eventually triumph over it. Maybe so, maybe not. But how pretty it is to believe it may. And how pleasurable it is to be absorbed into the bloodstream of this movie and be borne along on its racing pulse...

Author: /time Magazine | Title: CINEMA: ONCE MORE WITH FEELING | 11/6/1995 | See Source »

...sentimentality that verges at times on the woozy," says Schickel. "Yet, it's more sophisticated than the feelings it evokes, and infinitely more compelling than you can imagine a film derived from such a familiar source might be. How pleasurable it is to be absorbed into the bloodstream of this movie and be borne along on its racing pulse...

Author: /time Magazine | Title: MOVIES . . . LES MISERABLES | 10/27/1995 | See Source »

...William Sandborn offered an unusual treatment. He gave the 23-year-old college student a nicotine patch as part of a study to determine its effect on colitis. Normally prescribed to help smokers kick the habit, these patches release a predetermined amount of nicotine through the skin into the bloodstream, where it eases the craving for cigarettes. Physicians have known for some time, however, that nicotine also seems to quiet the symptoms of colitis. So, although the Food and Drug Administration has not approved the nicotine patch for the treatment of colitis, Sandborn thought it might just do the trick...

Author: /time Magazine | Title: DOUBLE-DUTY DRUGS | 9/18/1995 | See Source »

...three separate teams of researchers, including Friedman's, have confirmed that this protein is indeed the blood factor that makes fat mice thin. But they are still trying to puzzle out just how it works. Friedman, for one, believes leptin is almost certainly a hormone that travels through the bloodstream to act on the brain. In fact, it appears leptin may act in a feedback loop like the temperature sensor in a thermostat--or in this case a "fatstat"--to tell the body whether to turn metabolism and appetite up or down. Thus when leptin is low, hunger pangs increase...

Author: /time Magazine | Title: WEIGHT-LOSS NIRVANA? | 8/7/1995 | See Source »

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