Word: bloodstream
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Treatment to stop the growth of malignant tumors may come from a protein in the tumors themselves, researchers have found. Scientists at the Children's Hospital discovered that angiostatin -- a protein produced by large, growing tumors -- inhibits the growth of tiny secondary tumors that spread through the bloodstream and often lodge in vital organs such as the lungs, liver and brain. While the study's authors caution that this isn't a cure for cancer, they're optimistic that the protein will someday be used to slow or stop the growth of cancerous tumors...
...where TB germs have taken hold, including the lungs or the bones. With staph or strep, the sheer volume of disease-fighting immune cells can overload blood vessels, ripping tiny tears in the vessel linings; toxins can also damage the vessels directly. Plasma begins to leak out of the bloodstream; blood pressure drops, organs fail, and the body falls into a state of shock. In cholera, bacterial toxins attack intestinal cells, triggering diarrhea, catastrophic dehydration and death...
...long anticipated. Just past midnight last Tuesday, the man who tortured and murdered 33 young men and boys during the 1970s would be executed by lethal injection at the Stateville penitentiary in Joliet, Illinois. Justice would be served, swift and clean, as three chemicals were introduced intravenously into his bloodstream. The first drug would knock him out, the second would suppress his breathing, the last would stop his heart. The procedure would take no more than five minutes. But Gacy would take 18 minutes to die. A clog developed in the delivery tube attached to his arm. Gacy snorted just...
...much smaller than a BB," says Dr. Judah Folkman of Harvard Medical School. This tiny mass -- known as a carcinoma in situ, literally cancer in place -- is malignant, but not yet dangerous. Why? Because the cells at the center of the tumor are too far from the bloodstream to obtain essential nutrients, they are less vigorous. Like a society with zero population growth, a carcinoma in situ adds about as many new cells as it loses old ones...
Angiogenesis is the harbinger of metastasis. The same vessels that feed the tumor also provide it with avenues of escape. Not all the myriad cells shed by tumors survive the turbulent voyage through the bloodstream, notes experimental oncologist Ann Chambers of the London Regional Cancer Centre in Ontario. But those that do eventually slip through blood-vessel walls with ease. Using a video camera attached to a microscopic lens, Chambers has watched in wonder as melanoma and breast-cancer cells, injected into mice, become lodged in capillary walls, then crawl out into the liver. Three days later, her camera resolves...