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Moral indignation did and still does affect me in a direct physical manner," he once confessed. "I can feel, during an attack, the infusion of adrena line into the bloodstream, the craving of the muscles for violent action." For most of this century, Arthur Koestler lived by those words. Last week at his home in London, he died by them at the age of 77. The "rootless cosmopolitan," as he styled himself, had been an ardent supporter of "autoeuthanasia," and when the suffering of old age and disease grew in supportable, he reportedly took a lethal dose of drugs...

Author: /time Magazine | Title: Rootless Cosmopolitan of the Age | 3/14/1983 | See Source »

...birth-control pill. It does not, however, contain estrogen, and therefore does not seem to share the most serious drawbacks of the Pill: increased risk of abnormal blood clots and heart attacks. Depo-Provera can have less serious side effects that persist as long as it is in the bloodstream. Among them: weight gain, loss of sex drive, menstrual irregularities and, frequently, complete cessation of menstrual bleeding. According to Upjohn Research Manager Gordon Duncan, none of these problems are serious enough "to preclude its use as a contraceptive...

Author: /time Magazine | Title: Medicine: Effective, but How Safe? | 1/24/1983 | See Source »

...drugs are anti-inflammatory agents like aspirin but remain in the bloodstream six times as long. Thus they are effective as once-a-day doses. They are also less apt to irritate the digestive tract. According to Lilly, Oraflex causes 50% fewer gastrointestinal side effects than aspirin. There remains a drawback. In clinical trials, Oraflex caused sun sensitivity leading to an itchy rash in about 20% of patients. This can be prevented by applying sunscreen lotions or even by getting a protective suntan before using the drug...

Author: /time Magazine | Title: Medicine: Fighting Arthritis Pain | 5/31/1982 | See Source »

...link between ovulation and exercise may also involve a natural opium-like substance, beta-endorphin, that pours into the bloodstream during stressful workouts. Beta-endorphin has been shown to suppress female hormones regulating the menstrual cycle. In any case, for women runners being treated for infertility, good advice seems to be: stop running...

Author: /time Magazine | Title: Medicine: Running Woe | 1/25/1982 | See Source »

...colleagues, blood plasma is removed from a patient and run through a device containing beads of charcoal coated with protein A, a component of the staph bacteria. The plasma is then returned to the patient. The scientists speculate that the bacterial protein somehow alters substances carried in the bloodstream that were paralyzing the body's natural defenses...

Author: /time Magazine | Title: Medicine: Capsules: Dec. 14, 1981 | 12/14/1981 | See Source »

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