Word: bonadonna
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...degree of spreading (measured by counting the number of malignant lymph nodes), radiation treatment is strongly recommended. Women with more extensive spreading may also be candidates for a lumpectomy, but for these patients chemotherapy might be used as an added safeguard. According to Veronesi's colleague, Dr. Gianni Bonadonna, a leading authority on chemotherapy, there is really only one reason for a complete mastectomy: when the tumor is so large that it fills one-third or more of the breast. In that case, he asks, "What would you be leaving behind...
...success rates for early detection of tumors, many women are so terrified by the prospect of a mastectomy that they delay treatment. As former Patient Judy Feinman, 46, puts it: "I knew there was something wrong, but I just didn't want to face it." Perhaps, says Bonadonna, the availability of less disfiguring treatments will lead to less procrastination. "Women will realize that if they come in early, they will not be punished by the removal of a breast.'' -By Claudia Wallis. Reported by Mary Carpenter/Venice and Carol Foote/Santa Cruz
...pioneering therapy was developed by researchers at Milan's Istituto Nazionale Tumori, the Italian equivalent of the U.S. National Cancer Institute (which supported the study). Led by Dr. Gianni Bonadonna, who studied at Manhattan's Memorial Sloan-Kettering Cancer Center in the 1960s, the Milan team picked three drugs-cyclo-phosphamide, methotrexate and 5-fluorouracil (CMF). All were known to interfere with the growth of cells, especially of fast-multiplying cancer cells. But they proved to be more active than when used alone...
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