Word: bone-marrow
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...about curing infected patients, focusing instead on treatment and prevention. But in an announcement that caused a flutter of excitement and a wave of prudent skepticism, Berlin-based hematologist Gero Huetter claimed on Thursday that he has cured an HIV infection in a 42-year-old man through a bone-marrow transplant...
...patient, a U.S. citizen living in Germany, was suffering from advanced leukemia and HIV two years ago when Huetter treated the cancer with a bone-marrow transplant at Berlin's Charité hospital. As a side experiment, he inserted the bone marrow of a donor naturally resistant to HIV, the virus that causes AIDS. (Researchers have long known that about 1% of Europeans carry a genetic mutation that makes their cells resistant to HIV infection.) Bone marrow produces the cells that HIV attacks. So, the thinking went, inserting marrow that produces HIV-resistant cells might endow the patient with...
...Pharma's arsenal result from that understanding. Gleevec, for instance, treats one form of leukemia by zeroing in on the Philadelphia (Ph) chromosome, that part of the genome that directs bone marrow to keep making abnormal white blood cells. Because of drugs like Gleevec and therapies such as bone-marrow and stem-cell transplants, there are 12 million people walking around today who are classified as survivors...
...their three grown children (Anne Consigny, Mathieu Amalric, Melvil Poupaud) and their kids for the sort of holiday games you'll find in many family reunions: musical beds, generational scores-settling and the ripping off of psychic scabs. Amid all the melodrama - Junon has liver cancer and needs a bone-marrow transplant from someone of her blood - the conversation is bantering, often affectionate. In this chatty 2-1/2hr. film, Desplechin (Kings and Queen) seems to be going for the old French New Wave recipe of emotional warmth and cinematic wizardry. But the souffl? doesn't quite rise. This...
...checkmark offered a lifeline. Last May, Beninati received a transplant of stem cells harvested from the blood of an infant's discarded umbilical cord at Boston's Dana Farber Institute, to help him fight a rare blood condition called myelodysplastic syndrome. After doctors couldn't find a matching bone-marrow donor, the 58-year-old New Yorker says his last hope was cord blood, a solution that would not exist without parental donors. New parents, Beninati urges, "must understand the importance this decision can mean for the public good...