Word: bone
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Dates: during 1980-1989
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...already up to interleukin-7 and interleukin-8," says Immunologist Lloyd Old, of the Memorial Sloan-Kettering Cancer Center in Manhattan, "and one can expect that we will go on from there." Scientists have so far discovered at least five different colony-stimulating factors, which cause cells in the bone marrow to mature and differentiate into red and white blood cells. Each of the players seems to have a vital, if sometimes overlapping, role...
Using bioengineering techniques, medical researchers have begun to mass- produce these substances and use them, sometimes in combined "cocktails," to boost the immune system against specific diseases. In clinical trials at Boston's New England Deaconess Hospital, Dr. Jerome Groopman has found that granulocyte-macrophage colony-stimulating factor reverses bone-marrow failure and boosts white-cell counts in AIDS patients. Gamma interferon seems to remedy the defective functioning of monocytes and macrophages in a wide variety of diseases. Alpha interferon has been particularly effective against two types of leukemia and non-Hodgkin's lymphoma, a cancer of the lymph system...
...which both B cells and T cells are lacking. The most famous SCID victim, a Texas boy named David, lived for twelve years in a germ-free bubble while doctors searched in vain for a cure for his disease. He died in 1984, four months after receiving a bone-marrow transplant that doctors hoped would supply his missing immune cells...
...free-associate: Andy Warhol and what? Close your eyes. Do silver-and- rosewood tea sets come to mind? How about a Superman Touch-Tone phone or a frontal photo of a naked Yul Brynner? Allow your imagination to wander across Eskimo bone masks, prehistoric pottery and World War II medals. Try these: 18- karat-gold nail scissors and wooden merry-go-round horses...
...ailment, as its name suggests, is generally traceable to an impairment of one or both of the temporomandibular joints. These olive-size structures, composed of bone and a cushioning cartilage disk, are located at the points where the jaw meets the skull. TMJ may be triggered by infection, arthritis, a blow to the head, shouting at a football game, even chomping on a bagel. A major contributing factor is emotional stress that leads to teeth clenching or grinding. Excruciating pain radiating through the head and neck, earaches and muscle spasms are the most frequent complaints...