Search Details

Word: boning (lookup in dictionary) (lookup stats)
Dates: all
Sort By: most recent first (reverse)


Usage:

...about curing infected patients, focusing instead on treatment and prevention. But in an announcement that caused a flutter of excitement and a wave of prudent skepticism, Berlin-based hematologist Gero Huetter claimed on Thursday that he has cured an HIV infection in a 42-year-old man through a bone-marrow transplant...

Author: /time Magazine | Title: Can a Bone-Marrow Transplant Halt HIV? | 11/13/2008 | See Source »

...patient, a U.S. citizen living in Germany, was suffering from advanced leukemia and HIV two years ago when Huetter treated the cancer with a bone-marrow transplant at Berlin's Charité hospital. As a side experiment, he inserted the bone marrow of a donor naturally resistant to HIV, the virus that causes AIDS. (Researchers have long known that about 1% of Europeans carry a genetic mutation that makes their cells resistant to HIV infection.) Bone marrow produces the cells that HIV attacks. So, the thinking went, inserting marrow that produces HIV-resistant cells might endow the patient with...

Author: /time Magazine | Title: Can a Bone-Marrow Transplant Halt HIV? | 11/13/2008 | See Source »

...this a viable cure for HIV? Not by a long shot. Even Huetter says bone-marrow transplants, which kill about a third of patients, are so dangerous that "they can't be justified ethically" in anything other than desperate situations like late-stage leukemia. Nor is it clear that Huetter's claim to have cured his patient is yet justified. HIV has a frustrating ability to hide in hard-to-detect "reservoir" cells in various parts of the body. Current antiviral drugs, for example, can lower a patient's "viral load" to the point that HIV is undetectable...

Author: /time Magazine | Title: Can a Bone-Marrow Transplant Halt HIV? | 11/13/2008 | See Source »

...there might be a glimmer of hope in the case. If the transplant does prove to have been a success and can be replicated, researchers say gene therapists might one day be able to re-engineer a patient's cells to change their bone marrow the same way a transplant does, except without the dangers. Such a breakthrough, if it proves possible, would be "decades rather than years away," according to Ade Fakoya, a London-based clinician and senior adviser to the nonprofit Aids Alliance. The treatment would also likely prove too expensive to implement in developing countries where...

Author: /time Magazine | Title: Can a Bone-Marrow Transplant Halt HIV? | 11/13/2008 | See Source »

...Noble of the British AIDS charity Avert says recent setbacks for research into an AIDS vaccine, along with multiple false hopes in the search for a cure, have caused many in the HIV activism community to view Huetter's experiment warily. For many AIDS activists, bone-marrow transplantation is a loaded procedure that evokes a traumatic past: before antivirals were widely introduced in the 1990s, it was one of the aggressive and often fatal procedures doctors tried in their desperate effort to halt the epidemic; some of these transplants even used marrow harvested from baboons...

Author: /time Magazine | Title: Can a Bone-Marrow Transplant Halt HIV? | 11/13/2008 | See Source »

Previous | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | Next