Word: boning
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Calcium supplements, unfortunately, cannot prevent osteoporosis after menopause. At the Bethesda meeting, researchers reported on eight studies that found extra calcium had little or no effect in slowing bone loss, even / when the dosage was as high as 3,000 mg per day. The most effective defense against osteoporosis in these women, all agreed, is estrogen replacement. Such therapy has been linked in the past to an increase in endometrial cancer, but doctors now believe the risk can be minimized by tandem use of progesterone- like hormones...
Moreover, researchers point out, although calcium does help build bone and retain it, the mineral is simply one factor in lifelong skeletal health. Some studies have found bone loss is slower in those who engage in such weight-bearing physical activities as running and walking. In one survey, women ages 35 to 65 who took a 50-minute aerobics class three times a week lost only 2.5% of the density in their forearm bones, compared with 9.5% for women who did not exercise. "Osteoporosis is a total life-style problem," emphasizes Heaney. "You can't cure a bad life-style...
...take steps that could help ward off the disease. Says Dr. John Eisman, who led the groundbreaking research at the Garvan Institute & of Medical Research in Sydney: "I envision a woman going in for a blood test, which will become as routine as a cholesterol check, to assess her bone density and risk for osteoporosis...
...report to Nature, the researchers announced that they have found two versions of a specific gene that are associated with varying bone density. One type, which they dubbed "b," is linked with stronger skeletons, and the other, labeled "B," with weaker ones. The gene itself directs construction of receptors (docking sites within the cell) for a form of vitamin D that plays a crucial role in bone formation. Once vitamin D locks in, the receptors act as a sort of control tower, switching on and off other genes that regulate calcium absorption and the constant renewal of bone...
Until about age 35, the body synthesizes new skeletal tissue faster than it dies. Then the balance reverses, with bone being lost faster than it is replaced. In osteoporosis, that normal wasting away reaches such a hazardous level that bones become fragile. They lose their usual spongelike appearance and are more like porous lace. While both men and women experience bone loss, women are much more susceptible to osteoporosis. Bone deteriorates faster after menopause, probably in part because of a sharp drop in levels of the hormone estrogen...