Word: bowel
(lookup in dictionary)
(lookup stats)
Dates: during 1960-1969
Sort By: most recent first
(reverse)
...still cannot agree on how good the vaccines are, or how to make the best one. Though injections of killed bacilli, as in the vaccines now generally used, stimulate the production of antibody in the blood, they seem to have little effect on multiplication of bacilli in the small bowel, where they do their damage before being excreted to infect a new host. Dr. Mukerjee is working on a vaccine made from live but harm less varieties of El Tor, which would be taken by mouth and would, he believes, protect the bowel...
...cholera fighter, has pursued his interest in the disease since 1955. An important development was his theory that the diarrhea results from a disturbance of what doctors call "the sodium pump." Normally, Dr. Phillips explains, sodium salts and other electrolytes pass in both directions from the inside of the bowel into the blood plasma, and vice versa; and in healthy people the movement is greater from the gut to the plasma. In cholera, the proportions are reversed. But is this because one goes up, or the other down, or both? Experiments with himself and his teammates as subjects heroically submitting...
Satisfied that both diet and drugs had already been tried, Dr. Troncelliti decided on heroic measures. He prescribed a jejuno-colostomy (short-circuiting most of the small bowel), an operation devised in 1912 for patients suffering from incurable metabolic defects. Because the body absorbs most of its fats through the wall of the lower small bowel, by drastically shortening that absorbing wall the surgeon hoped to limit his patient's assimilation of fat calories...
Blind Loop. Dr. Troncelliti opened the man's abdomen and cut the small bowel about 42 inches below the point where it emerges from behind the large bowel (see diagram). He took the free end of this 42-inch loop and stitched it into the side of the transverse colon, leaving the remaining 15 to 20 feet of the small bowel as a nonfunctioning blind loop. When the man recovered from the operation, he continued to overeat, but the food digested in his stomach and duodenum passed more directly into his colon. He absorbed enough protein and starch...
...Panacea. After such surgery, now standardized with a 30-inch loop of jejunum, most patients suffer from some diarrhea, and at best must expect to have three or four bowel movements daily. This is not a high price to pay for the dramatic benefits, Dr. Troncelliti suggested in his report to the annual congress of the American College of Surgeons last week. At the same time, he emphasized that he is not recommending this "super-surgery as a panacea for the super-obese." To qualify as a candidate for jejuno-colostomy, a patient must be at least 100 lbs. overweight...