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...still cannot agree on how good the vaccines are, or how to make the best one. Though injections of killed bacilli, as in the vaccines now generally used, stimulate the production of antibody in the blood, they seem to have little effect on multiplication of bacilli in the small bowel, where they do their damage before being excreted to infect a new host. Dr. Mukerjee is working on a vaccine made from live but harm less varieties of El Tor, which would be taken by mouth and would, he believes, protect the bowel...

Author: /time Magazine | Title: Infectious Diseases: Cholera Resurgent | 12/3/1965 | See Source »

Satisfied that both diet and drugs had already been tried, Dr. Troncelliti decided on heroic measures. He prescribed a jejuno-colostomy (short-circuiting most of the small bowel), an operation devised in 1912 for patients suffering from incurable metabolic defects. Because the body absorbs most of its fats through the wall of the lower small bowel, by drastically shortening that absorbing wall the surgeon hoped to limit his patient's assimilation of fat calories...

Author: /time Magazine | Title: Surgery: Bypassing the Small Bowel | 10/29/1965 | See Source »

Blind Loop. Dr. Troncelliti opened the man's abdomen and cut the small bowel about 42 inches below the point where it emerges from behind the large bowel (see diagram). He took the free end of this 42-inch loop and stitched it into the side of the transverse colon, leaving the remaining 15 to 20 feet of the small bowel as a nonfunctioning blind loop. When the man recovered from the operation, he continued to overeat, but the food digested in his stomach and duodenum passed more directly into his colon. He absorbed enough protein and starch...

Author: /time Magazine | Title: Surgery: Bypassing the Small Bowel | 10/29/1965 | See Source »

...Panacea. After such surgery, now standardized with a 30-inch loop of jejunum, most patients suffer from some diarrhea, and at best must expect to have three or four bowel movements daily. This is not a high price to pay for the dramatic benefits, Dr. Troncelliti suggested in his report to the annual congress of the American College of Surgeons last week. At the same time, he emphasized that he is not recommending this "super-surgery as a panacea for the super-obese." To qualify as a candidate for jejuno-colostomy, a patient must be at least 100 lbs. overweight...

Author: /time Magazine | Title: Surgery: Bypassing the Small Bowel | 10/29/1965 | See Source »

...detailed exegesis of the President's September 1955 heart attack and seven-week recuperation. "Every American family has had a heart attack in it," reasoned Hagerty. "People are deeply interested in the President's recovery." Thus, White House aides released such minutiae as his rectal temperature and bowel movements, embarrassing as many citizens as they reassured...

Author: /time Magazine | Title: Nation: The World at His Bedside | 10/15/1965 | See Source »

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