Word: braine
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Dates: during 1990-1999
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...first glance, these stories seem completely unrelated--three profoundly different disorders treated with three different drugs. Yet all three medications have one crucial element in common: they target the brain chemical serotonin. Though serotonin has been known to researchers for nearly a half-century, only in recent years have neuroscientists begun to understand how important this one substance is to the functioning of the human psyche. Serotonin, or the lack of it, has been implicated not only in depression, uncontrollable appetite and obsessive-compulsive disorder but also in autism, bulimia, social phobias, premenstrual syndrome, anxiety and panic, migraines, schizophrenia...
...pamphlet they distributed described a number of experiments they say are carried out at the center, including forced artery blockages in baboons, brain damage in infant primates and the administration of cocaine to squirrel monkeys...
Biochemically, hypericum has some interesting properties. For starters, says University of Frankfurt psychopharmacologist Walter Muller, it appears to affect the brain in the same way Prozac does--by prolonging the activity of the mood-enhancing brain chemical serotonin. This is the same neurotransmitter acted on by the controversial diet pills fen-phen and Redux (see following story). But hypericum has much broader activity. In rats and mice, at least, it extends the action of at least two other powerful brain chemicals that are thought to play a role in depression: dopamine and norepinephrine. In each case, hypericum appears to work...
...been taking fen-phen for less than a month died of primary pulmonary hypertension, a sometimes fatal lung condition already associated with Redux. And an article in the Journal of the American Medical Association last month confirmed earlier reports that both fen-phen and Redux can cause brain damage in lab animals...
...Doktor's comic genius may be what really routs your brain. "Yes it is many times you doubt on the human" takes the background music from a televised real estate catalog and plays a sample of fiendishly incomprehensible speech with Jamaican-English rhythms. You'll spend hours trying to decipher it and may, in fact, go insane. ("Sweet love for my nation?" Perhaps...