Word: braine
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Dates: during 2000-2009
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That discrepancy is not unheard of: many elderly patients develop the brain lesions, plaques and tangled neurological-tissue fibers that are indicative of dementia and Alzheimer's disease, but not all of them exhibit the memory loss and confusion that typically characterize these disorders. In fact, the number of such patients may be greater than researchers first thought. In a November 2008 study, a team of scientists used a new positron emission tomography (PET) brain-imaging technique developed by Drs. William Klunk and Chester Mathis of the University of Pittsburgh to image the brains of live patients - a leap forward...
...leading theory to explain this fortunate disconnect is the brain-reserve hypothesis, which suggests that people who have more cognitive ability and more neural tissue to start with - sharper minds, broadly - may be better able to withstand the ravages of age. "In some ways, you could think of it like a trained athlete who might be able to resist some atherosclerosis of the heart," explains Dr. Bradley Hyman, director of the Massachusetts Alzheimer's Disease Research Center and a professor of neurology at Harvard Medical School...
Past studies have shown that patients who have so-called asymptomatic Alzheimer's disease - those who have the hallmark brain lesions and plaques of Alzheimer's disease but no memory loss - also have enlarged neurons, compared with patients who suffer cognitive impairment. Dr. Diego Iacono, a neuropathology fellow at Johns Hopkins School of Medicine and the future director of the Brain Bank at Sweden's Karolinska Institute, conducted several such studies in predominantly male populations, but his latest research, the study published in Neurology, demonstrates the same patterns in an entirely female population - of nuns. (See pictures of the sisters...
...bring out the worst in other people. And Brüno's basic m.o., like Borat's, is to go into the world with a camera to bewilder and infuriate people, never failing to prove that anger and stupidity are the permanent default modes of the human brain...
...talk in the book about a drug study in which they administered painkillers, and when they told patients the drugs had been bought at discount, they were actually less effective. That's kind of terrifying. The response to a discount is profound in the human brain. What is less profound is the response to actually owning that object once you get the discount. We strive to get that deal, but we tend to devalue the object after we purchase it. For many things, the biggest charge we get is that transaction itself. Retailers and marketers strive to make us think...