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Overloading the body with too many calories and keeping insulin levels high short-circuits this loop and can lead to insulin resistance and Type 2 diabetes, in which organs no longer respond to changing insulin levels. The result: a brain and body that are constantly hungry and in need of more food. Disrupting the insulin threshold usually takes decades--which explains why this form of diabetes was generally more common in adults over age 30 and why the more genetically driven Type 1 diabetes was more prevalent among children. Before 1994, only about 5% of school-age children with...

Author: /time Magazine | Title: Overweight Children: Living Large | 6/12/2008 | See Source »

When writer-director Andrew Stanton--whose last film was Pixar's all-time box-office champ, Finding Nemo--showed the first reels of WALL?E to the studio's brain trust three years ago, fellow auteur Brad Bird (The Incredibles) told him, "Man, you didn't make it easy for yourself." A movie that shows but doesn't tell, and whose leading characters are essentially mimes, could put an end to the eight-film box-office winning streak that began with Toy Story in 1995 and continued unbroken through last year's Ratatouille. To sell the project, Stanton had only...

Author: /time Magazine | Title: WALL-E: Pixar's Biggest Gamble | 6/12/2008 | See Source »

After New York Governor Eliot Spitzer was busted as Client No. 9 of the Emperors Club prostitution ring, the first and simplest question pundits asked was, Why do powerful men do this? (New York magazine succinctly answered with a picture of Spitzer, the label brain and an arrow pointing to his crotch.) Next came, Why do their wives stand by them?, for which many thinkers offered many theories...

Author: /time Magazine | Title: TV's Call Girl | 6/12/2008 | See Source »

...other customers like you have bought. They shovel through data about millions of buyers and tens of millions of sales and then, like the shopkeepers, come up with a suggestion. However, the computers don't do all this in a 1,400-g (3 lb.), walnut-wrinkled mass of brain tissue but in a vast network of computers. It's easy to say that one approach is more complex than the other. It's a lot harder to say which...

Author: /time Magazine | Title: The Art of Simplexity | 6/12/2008 | See Source »

...world. "Ask me why I forgot my keys today, and the answer may be that something was on my mind," says neuroscientist Chris Wood of the Santa Fe Institute (SFI) in New Mexico, a multidisciplinary think tank devoted to complexity theory. "Ask me about the calcium channels in my brain that drive remembering, and you're asking a much harder question...

Author: /time Magazine | Title: The Art of Simplexity | 6/12/2008 | See Source »

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