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...mere metabolic side effect - is irrelevant. What they believe is that it can be therapeutically exploited. The theory is simple: If most aggressive cancers rely on the fermentation of sugar for growing and dividing, then take away the sugar and they should stop spreading. Meanwhile, normal body and brain cells should be able to handle the sugar starvation; they can switch to generating energy from fatty molecules called ketone bodies - the body's main source of energy on a fat-rich diet - an ability that some or most fast-growing and invasive cancers seem to lack...

Author: /time Magazine | Title: Can a High-Fat Diet Beat Cancer? | 9/17/2007 | See Source »

...other therapeutic options." That means that most people in the study are faring very badly to begin with. All have exhausted traditional treatments, such as surgery, radiation and chemo, and even some alternative ones like hyperthermia and autohemotherapy. Patients in the study have pancreatic tumors and aggressive brain tumors called glioblastomas, among other cancers; participants are recruited primarily because their tumors show high glucose metabolism in PET scans...

Author: /time Magazine | Title: Can a High-Fat Diet Beat Cancer? | 9/17/2007 | See Source »

Past studies, however, offer some hope. The first human experiments with the ketogenic diet were conducted in two children with brain cancer by Case Western Reserve oncologist Linda Nebeling, now with the National Cancer Institute. Both children responded well to the high-fat diet. When Nebeling last got in contact with the patients' parents in 2005, a decade after her study, one of the subjects was still alive and still on a high-fat diet. It would be scientifically unsound to draw general conclusions from her study, says Nebeling, but some experts, such as Boston College's Thomas Seyfried...

Author: /time Magazine | Title: Can a High-Fat Diet Beat Cancer? | 9/17/2007 | See Source »

...near death experience is the ultimate fight-or-flight response from a brain experiencing a massive adrenaline rush. This ignites a cascade of neuronal activity, producing a sound-and-light show of our past experiences. As these energy waves subside, time appears to be stretched, allowing a longer than expected experience of this vivid imagery. Gajinder Oberoi, Hobart...

Author: /time Magazine | Title: Inbox | 9/14/2007 | See Source »

...layman's terms [Sept. 10]. I had a cardiac arrest in 2003 and was resuscitated by well-trained paramedics. I did not have a near-death experience, just the total blankness of a deep sleep. I believe NDEs are caused by malfunctions of consciousness arising from an oxygen-starved brain. The forms NDEs take are influenced by culture and by religious beliefs. I don't think any non-Christian, for example, would see a tunnel lit by brilliant white light and a Christ-like figure in a white robe. George Varghese, Nairne, South Australia...

Author: /time Magazine | Title: Inbox | 9/14/2007 | See Source »

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