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...EXTREME EXAMPLE OF HOW CHANGES IN the input reaching the brain can alter its structure is the silence that falls over the somatosensory cortex after its owner has lost a limb. Soon after a car crash took Victor Quintero's left arm from just above the elbow, he told neuroscientist V.S. Ramachandran of the University of California at San Diego that he could still feel the missing arm. Ramachandran decided to investigate. He had Victor sit still with his eyes closed and lightly brushed the teenager's left cheek with a cotton swab...

Author: /time Magazine | Title: The Brain: How The Brain Rewires Itself | 1/19/2007 | See Source »

...brushed, Victor said. A spot just below Victor's left nostril caused the boy to feel a tingling on his left pinkie. And when Victor felt an itch in his phantom hand, scratching his lower face relieved the itch. In people who have lost a limb, Ramachandran concluded, the brain reorganizes: the strip of cortex that processes input from the face takes over the area that originally received input from a now missing hand. That's why touching Victor's face caused brain to "feel" his missing hand...

Author: /time Magazine | Title: The Brain: How The Brain Rewires Itself | 1/19/2007 | See Source »

...regions of cortex that handle sensations from the feet abut those that process sensations from the surface of the genitals, some people who have lost a leg report feeling phantom sensations during sex. Ramachandran's was the first report of a living being knowingly experiencing the results of his brain rewiring...

Author: /time Magazine | Title: The Brain: How The Brain Rewires Itself | 1/19/2007 | See Source »

...SCIENTISTS PROBE the limits of neuroplasticity, they are finding that mind sculpting can occur even without input from the outside world. The brain can change as a result of the thoughts we think, as with Pascual-Leone's virtual piano players. This has important implications for health: something as seemingly insubstantial as a thought can affect the very stuff of the brain, altering neuronal connections in a way that can treat mental illness or, perhaps, lead to a greater capacity for empathy and compassion. It may even dial up the supposedly immovable happiness set point...

Author: /time Magazine | Title: The Brain: How The Brain Rewires Itself | 1/19/2007 | See Source »

When OCD patients were plagued by an obsessive thought, Schwartz instructed them to think, "My brain is generating another obsessive thought. Don't I know it is just some garbage thrown up by a faulty circuit?" After 10 weeks of mindfulness-based therapy, 12 out of 18 patients improved significantly. Before-and-after brain scans showed that activity in the orbital frontal cortex, the core of the OCD circuit, had fallen dramatically and in exactly the way that drugs effective against OCD affect the brain. Schwartz called it "self-directed neuroplasticity," concluding that "the mind can change the brain...

Author: /time Magazine | Title: The Brain: How The Brain Rewires Itself | 1/19/2007 | See Source »

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