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Each of these compounds is slightly different, and scientists are just beginning to figure out how they all work together (see diagram). What is clear is that all of them are important nodes along an elaborate network of interconnecting pathways that feed into, and out of, the hypothalamus, a brain structure that is the control center for weight regulation. The body produces hormones that activate the hypothalamus. The neurons in the hypothalamus send new messages back to the body. And just like subliminal messages spliced into a filmstrip, these signals powerfully affect our behavior even when we are not aware...

Author: /time Magazine | Title: Cracking the Fat Riddle | 9/2/2002 | See Source »

...complicated. Not only do the other hormones of the digestive system play a role, but also researchers are learning that they must account for the influence of such mood-altering neurotransmitters as dopamine and serotonin, as well as the stress hormones adrenaline and cortisol. And then there are melanocortins, brain chemicals whose power to affect weight loss and gain is just now coming into focus...

Author: /time Magazine | Title: Cracking the Fat Riddle | 9/2/2002 | See Source »

...labor mightily to obtain a sugar pellet even after they have dined on rat chow and aren't particularly hungry. The reason, thinks Allen Levine, director of the University of Minnesota's obesity center, has a lot to do with sugar's impact on mood-enhancing circuits in the brain. Sugar gives rats--and by extension humans--a buzz...

Author: /time Magazine | Title: Cracking the Fat Riddle | 9/2/2002 | See Source »

...particularly disturbing page. "A 22-year-old woman is in the emergency room with a gunshot wound to the head," my chief resident told me. "Oh, and it looks self-inflicted," he added. The woman, a recent college grad, was in a coma and starting to show signs of brain death. I knew that an immediate operation was her best chance for survival. Over the next several hours, we worked feverishly to preserve the life she had tried to throw away...

Author: /time Magazine | Title: When the Young Take Their Lives | 9/2/2002 | See Source »

DIED. DR. MARNIE ROSE, 28, of brain cancer. Her battle against the tumor was followed by millions on the six-week ABC reality series Houston Medical...

Author: /time Magazine | Title: Milestones Sep. 2, 2002 | 9/2/2002 | See Source »

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