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...type of brain scan helps identify structures that are the wrong size or shape. Two years ago, researchers at the University of Pittsburgh showed that the amygdalas of a group of overanxious young children were, on average, much larger than those of their unaffected peers. Perhaps they just had more fear circuits to contend with? Neuroscientists are tempted to say yes, but they admit the conclusion is pretty speculative. Another group of researchers found that patients with post-traumatic stress disorder had a smaller hippocampus than normal. Perhaps their stressful experiences had somehow interfered with the hippocampus' ability to make...

Author: /time Magazine | Title: The Science Of Anxiety | 6/10/2002 | See Source »

Another type of brain scan tells scientists which brain cells are using the most oxygen or soaking up the most nutrients. The idea, explains Dr. Scott Rauch of Massachusetts General Hospital, is that any area that seems more active than usual while someone is anxious may play an important role in making the person that way. Rauch's team has spent the past eight years scanning groups of combat veterans, some with post-traumatic stress disorder and some without, to see which areas of the brain light up when they hear tapes recounting their most troubling memories...

Author: /time Magazine | Title: The Science Of Anxiety | 6/10/2002 | See Source »

...next step, Rauch says, is to scan groups of people who are likely to be thrust into dangerous situations--fire fighters, say, or police officers. Then it may be possible to determine if any changes in their brains are the result of traumatic situations or if the changes predate them. Either is plausible. The stress of surviving a building collapse, for example, could turn a normal amygdala into an overactive one. Or an already overactive amygdala may overwhelm the brain in the wake of a disaster...

Author: /time Magazine | Title: The Science Of Anxiety | 6/10/2002 | See Source »

There is plenty to learn about how anxiety and fear shape the brain. One of the biggest mysteries is the relationship between anxiety and depression. Researchers know that adults who suffer from depression were often very anxious as children. (It's also true that many kids outgrow their anxiety disorders to become perfectly well-adjusted adults.) Is that just a coincidence, as many believe, or does anxiety somehow prime the brain to become depressed later in life? Brain scans show that the amygdala is very active in depressed patients, even when they are sleeping. Studies of twins suggest that many...

Author: /time Magazine | Title: The Science Of Anxiety | 6/10/2002 | See Source »

...mistake, however, to think that pills alone can soothe your neurochemistry. Remember the cortex? That's where you would expect psychotherapy to work, increasing the repertoire of calming messages that can be passed along to the amygdala. Certain desensitization techniques can also help the brain learn, through the hippocampus, to be less reactive. Of course, you have to do it right. Reliving a trauma too soon after it happened could also make the memory harder to erase...

Author: /time Magazine | Title: The Science Of Anxiety | 6/10/2002 | See Source »

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