Word: brained
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Dates: during 2000-2009
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...Robben Island, Mandela would always include in his brain trust men he neither liked nor relied on. One person he became close to was Chris Hani, the fiery chief of staff of the ANC's military wing. There were some who thought Hani was conspiring against Mandela, but Mandela cozied up to him. "It wasn't just Hani," says Ramaphosa. "It was also the big industrialists, the mining families, the opposition. He would pick up the phone and call them on their birthdays. He would go to family funerals. He saw it as an opportunity." When Mandela emerged from prison...
...screen by Derek Haas, Michael Brandt and Chris Morgan, the white-collar drudge is Wesley Gibson (Scots actor James McAvoy), whose life is a conspiracy of indignities. In a job where he's badgered by his fat-cow boss, he reads a dense computer page and his brain isolates the words "why? "are? "you? "here?". His girlfriend is having sex with his best friend, and Wesley pays for the condoms his friend will use to betray him. Even his ATM sasses him. "Insufficient funds," the text brays at him. "You're an asshole." When he was an infant, his father...
...perfect political photo op - and this was a pretty darn good one -isn't aimed at the rational faculties of an informed electorate. It seeks whatever section of the brain it is that triggers a tummy rumble at the sight of a moist doughnut. It's about instinct, not reason...
...already being tested. Hagerman and a team at Chicago's Rush University Medical Center have begun trials with a drug called fenobam, originally designed as an antianxiety medication. MIT's Bear expects to begin trials with two other compounds later this year. The drugs target a receptor on brain cells that the fragile X protein normally helps regulate; the receptor, in turn, regulates proteins involved in learning and memory. "We're looking at a medication to reverse the retardation," says the optimistic Hagerman, "and I think we can achieve...
...times more message than normal," explains molecular biologist Paul Hagerman of the University of California at Davis, who together with wife Randi has received an NIH grant to study the disorder. Over time, messenger RNA--the substance that transcribes genes into proteins--accumulates in the nuclei of brain cells, eventually poisoning them...