Word: braining
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...Kennedy's seizure on Saturday has now been diagnosed as the result of a cancerous brain tumor. But his prognosis will depend on what doctors at Massachusetts General Hospital find as they continue their tests and weigh treatment options...
...biopsy of a suspicious growth in the 76-year-old senator's left parietal lobe revealed a malignant glioma, the most common type of brain tumor. It is diagnosed in some 25,000 Americans a year, and in 30% to 40% of cases, the first sign of the disease is a seizure - as was the case with Kennedy, who has been hospitalized since the weekend, but has not suffered another seizure. "Decisions regarding the best course of treatment for Senator Kennedy will be determined after further testing analysis," the senator's doctors said Tuesday in a statement. "He remains...
...chemotherapy agents that Kennedy and his doctors will most likely consider are Temodar, an oral drug, and Gliadel, a wafer embedded with a cancer-killing drug that surgeons place in the brain after the tumor is removed. The wafer dissolves over a period of two weeks and, if successful, destroys any remaining cancer cells in its wake. Radiation therapy for glioma usually begins two weeks following surgery, and lasts for about six weeks, says Dr. Henry Brem, director of neurosurgery at Johns Hopkins Hospital, who helped develop Gliadel and is not involved in Kennedy's treatment...
...made in people with Alzheimer's - which is made from a protein that all of us make, the amyloid precursor protein. [In people with Alzheimer's] that precursor protein is clipped by enzymes in the wrong place, and begins to form these little toxic parts that aggregate [in the brain] and eventually form fibrils and plaques that are the main pathologic feature of Alzheimer's disease. It's not clear why this happens exactly, and a lot of people have been studying it pretty hard. It's also not clear how much of this protein needs to be formed...
...cerebrovascular." That means that tests of the electrical activity of Kennedy's heart will be useful in isolating any potential abnormalities in his heart function, such as a slow heart rate or an irregular heartbeat, that could have contributed to the seizure. CAT scans and MRIs of the brain will also be needed to ensure that Kennedy's episode wasn't caused by a tumor or infection in the brain...