Word: brakes
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Leptin, which exercises an influence on appetite and thermogenesis, is thought to be key to maintaining this balance. For as we layer on fat, we pump out more leptin, which signals the hypothalamus that it's time to accelerate energy output and brake caloric intake. The problem is, people who gain weight have now been shown to develop a remarkable resistance to leptin's power. The fatter they get, and the more leptin they make, the more impervious the hypothalamus becomes. Eventually the hypothalamus interprets the elevated level of leptin as normal--and forever after misreads the drops in leptin...
...needed to power the car. Electric motors placed inside each wheel get the car rolling. Because the steering controls are all electronic--a concept known as "drive by wire"--gone, too, is the mechanical steering column. Instead, drivers rotate a small handgrip to accelerate and squeeze it to brake. "The basic premise is providing consumers with a design they can get passionate about, rather than asking them to compromise their lifestyles," says Christopher Borroni-Bird, director of "design and technology fusion...
Many others will experience the same exhilaration this year at the 30th Albuquerque bash, to be held Oct. 5-13 in Balloon Fiesta Park. About a million people are expected to attend, says fiesta director Pat Brake, with a showing of some 750 corporate, private and balloon-company vessels from 30 countries. As many as 60% of these balloon enthusiasts--spectators, passengers and pilots--are 50 or over, says Scott Appelman, president of Rainbow Ryders Inc., a full-service balloon company that is the official ride operator for the fiesta...
...showed that the anxiety response isn't necessarily caused by an external threat; rather, it may be traced to a breakdown in the mechanism that signals the brain to stop responding. Just as a car can go out of control due to either a stuck accelerator or failed brakes, it's not always clear which part of the brain is at fault. It may turn out that some anxiety disorders are caused by an overactive amygdala (the accelerator) while others are caused by an underactive prefrontal cortex (call it the brake...
...Perhaps you could point me out your favorite biker/leather bar?” I asked. The motorcycle jerked as Stith clutched and released the brake. The engine revved and we began an abrupt acceleration. Stith quickly informed me that she was deeply opposed to many of the common practices of motorcycle culture—most of all the entire notion of the biker bar, which she believes brings drinking and driving into uncomfortably close proximity...