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Such thorny human concerns are at the heart of a pioneering research effort that is bent on clinically identifying the long-term emotional and social effects of early genetic testing. Directed by neuropsychologist Jason Brandt of the Johns Hopkins University School of Medicine, the project enlists the talents of psychiatrists, psychologists, social workers, nurses, geneticists and ethicists to track the consequences of testing for the genetic mutation that causes deadly Huntington's disease. The program, says Brandt, "is seeking to determine how best to offer this test...

Author: /time Magazine | Title: SEEING THE FUTURE | 10/1/1997 | See Source »

...when a disease is nontreatable, the burden of knowing can overwhelm the benefits. Nationwide, only 1,500 genetic counselors, most of them drawing on guidelines derived from Brandt's research, have been trained to help people assess such risks. "The protocol developed by Brandt is a paradigm for other late-onset, incurable diseases," says Nancy Wexler, president of the Hereditary Disease Foundation and a leading HD researcher. "It's very responsive to individual needs...

Author: /time Magazine | Title: SEEING THE FUTURE | 10/1/1997 | See Source »

...Enter Brandt, 43, intelligent but unintimidating. Long fascinated by the physiological aspects of memory disorder, Brandt started delving into amnesia, Alzheimer's and dementia while a graduate student at Boston University. Upon joining the Johns Hopkins faculty in 1981, he began focusing on HD, a disease that he says provides "an almost unique opportunity to study how a deterioration of systems in the brain could result in cognitive, emotional and movement problems...

Author: /time Magazine | Title: SEEING THE FUTURE | 10/1/1997 | See Source »

...chief minister, Bertrand Osborne, resigned after the protests and was replaced Friday by a critic of British policy, David Brandt. Meanwhile Britain offered about $4,000 for each adult and $1,000 for each child who accepts a relocation package...

Author: /time Magazine | Title: UNDER THE VOLCANO | 9/1/1997 | See Source »

Sturdy and sophomore Rose Janowski should compete for Black's starting spot along with any incoming recruits. Even Brandt may get into the mix if the Crimson opts for a smaller lineup with Miller at the forward position. Add consistent reserves with ample game experience, and the Crimson looks solid once again...

Author: By Eduardo Perez-giz, | Title: W. Hoopsters Can't Lose in Ivies, Return to NCAAs | 6/5/1997 | See Source »

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