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Young established a second panel, which based its decision on two new studies showing that the heart's ability to pump blood increases after administration of t-PA. This indicates the drug can limit damage during a heart attack. However, says Harvard Cardiologist Eugene Braunwald, t-PA "has to be given within four to six hours after symptoms occur...

Author: /time Magazine | Title: Medicine: Go-Ahead for A Wonder Drug | 11/23/1987 | See Source »

...Darsee's co-authors, Blumgart Professor of Medicine Eugene Braunwald attacked the study in a commentary which accompanies it in Nature and in an interview yesterday...

Author: By Brooke A. Masters, | Title: More Errors Found In Work of Med School Prof | 1/16/1987 | See Source »

...Braunwald also said that the study does not present an accurate picture of the scientific world because it deals solely with papers Darsee worked...

Author: By Brooke A. Masters, | Title: More Errors Found In Work of Med School Prof | 1/16/1987 | See Source »

...Braunwald's work is just one example of the fascinating new technology being developed at Harvard for the prevention and treatment of heart attack. Braunwald, along with doctors around the country, is studying the effectiveness of a new drug which acts to dissolve blood clots inside the body. Since many heart attacks are caused by a clot which blocks the coronary artery and deprives the heart of its blood supply, the drug could potentially save thousands of lives...

Author: By Robert J. Wechsler, SPECIAL TO THE CRIMSON | Title: Playing Plumber With Our Arteries | 11/25/1985 | See Source »

...body in small amounts to prevent excessive clotting and to break down old clots that no longer serve any purpose. The Harvard researchers have used genetic engineering techniques to manufacture large quantities of t-PA, with the hope of bolstering the heart patient's anti-clotting mechanisms. According to Braunwald, "The aim is to use the body's own system to eliminate the clot before it can do too much damage to the heart...

Author: By Robert J. Wechsler, SPECIAL TO THE CRIMSON | Title: Playing Plumber With Our Arteries | 11/25/1985 | See Source »

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