Word: breakdown
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Dates: during 2000-2009
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...signals from one nerve cell to another. While most of the research attention in Alzheimer's has been on the build up of amyloid protein and tau tangles that strangle nerve function, the identification of PICALM suggests that some part of the disease may have to do with a breakdown in nerve-cell communication at the junctures. "If you had given people a list of genes and said which ones were involved in late onset Alzheimer's disease, PICALM would have been less likely than the others to be picked," says Goate...
...unexpected accessibility. The album opens at high energy, but the frenetic driving beat of the title track soon relaxes into a calm, agreeable record. An early highlight, “The End Is Near,” features a bluesy piano riff refreshing for its childlike simplicity. The guitar breakdown in follow-up track “Drive to Dallas” is one any shredder could be proud of, and its improbable fluctuations in energy showcase lead vocalist Eleanor Friedberger’s distinctive voice. At the Furnaces’ best, their songs sound like an exploration...
...hopes we'll someday balance it, play to self-interest to promote the national interest? Just as the Cash for Clunkers frenzy reached its peak, the Administration quietly released new deficit projections, which pointed to a $9 trillion gap over 10 years. In the middle of a national nervous breakdown over out-of-control spending, we took a summer break from puritanical fretting and got all excited about a federal subsidy for something we already buy more of than we need...
...constructed a pyramid to serve as your guide to the key food groups of the Square—burritos, pizza, burgers, ice cream, and The Kong. The pyramid is not designed to tell you what you should eat (it’s all basically unhealthy), but more of a breakdown of what you will...
...Here's the breakdown: The 230-m.p.g. number, according to GM's Frank Weber, global-vehicle-line executive for the Volt, is a measurement of the car's "city-driving cycle" - that's the 40 miles it can go without gas, plus one daily electric recharge, plus a little extra help from the gasoline it might need to continue to charge its batteries when they get low during driving in the city. It's basically measuring the Volt's electric-only-mode (with some help) mileage capacity. If the Volt got out on the highway - where it's powered largely...