Word: breast
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...among the thousands of American women who have survived breast cancer, you probably find yourself thinking twice about everything you do - what you eat, how much you exercise - to ensure that you don't increase your risk of developing another tumor. It's a natural response to a difficult diagnosis, but it can be challenging, especially when it comes to diet: most breast tumors are driven by the hormone estrogen, but estrogen is frequently found in many popular foods, from some types of milk and yogurt to breakfast bars to tofu and those addictive edamame beans...
...common culprit is soy, a plant that contains chemicals with estrogen-like and anti-estrogenic properties - making it a nutritional minefield for breast-cancer survivors. While Western diets are relatively low in soy - compared with the typical diet in Asia, where people eat soy daily - the percentage of Americans consuming soy at least once a week increased from 15% in 1997 to 28% in 2003. In the meantime, studies on the effect of soy on breast-cancer recurrence and mortality have been conflicting, with some showing that it can reduce risk, while others show an elevated rate of recurrent disease...
...largest study to date on soy's effect on breast cancer suggests that eating soy, even in large amounts, may not be harmful after all, and may even reduce recurrence and death from the disease. But while the findings are intriguing, not all doctors are ready to tout the benefits of tofu...
...based at Vanderbilt University and the Shanghai Institute of Preventive Medicine report data from the first four years of follow-up (total follow-up was five years) in the current issue of the Journal of the American Medical Association. The 5,042 women enrolled in the study were all breast-cancer survivors, ages 20 to 75, and they consumed soy from naturally occurring sources, such as tofu or soybeans; none of the women took soy supplements. They fell into two groups based on soy intake: those who consumed more than 15.3 g of soy protein a day, or as much...
Among the women consuming the most soy, the risk of death from breast cancer four years after diagnosis was 7.4% and the risk of recurrence was 8%. Women in the lower soy-intake group had higher risks: a 10.3% risk of death from breast cancer and an 11.2% risk of recurrence. "I think based on our study, I am quite comfortable saying that soy food, particularly a moderate amount, is safe, and potentially beneficial," says the study's lead author, Dr. Xiao-Ou Shu, an epidemiologist at Vanderbilt...