Word: breast
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...USPSTF, a volunteer group of 16 health professionals, is often considered to issue the most conservative recommendations compared with other national groups. In 2002, for instance, it called for breast-cancer screening every one or two years for women ages 40 to 49, while other guidelines advocated yearly tests. For its updated 2009 recommendations, the USPSTF analyzed clinical trials on the benefits of mammography - much of that same research was also evaluated for the task force's 2002 decision - while folding in new data on the risks and harms of screening. Those risks include false positive results, over-diagnosis, patient...
Overall, based on a review of mammography trials, the panel found that having a yearly mammogram screening cuts the risk of breast-cancer death 15% in women ages 40 to 49. That reduction, it should be noted, is relative, not absolute. The absolute risk of breast-cancer death after age 40 is 3% without annual screening, according to the computer models. That means that with routine screening, which leads to a 15% lower risk of death from breast cancer, a woman's absolute risk drops to 2.6%. Small numbers in either case. Put another way, the panel concluded, the benefit...
That benefit increases, however, with the age of the women being screened, as the risk of breast cancer rises: among women 50 to 59, one death is averted for every 1,339 women routinely screened; among women 60 to 69, 377 mammograms would be needed to prevent one death. The task force's computer models further showed that shifting women's screening schedule from yearly to once every two years retains 81% of the benefit of screening while reducing the harms like false positives by half...
...bound to get lost in a heated - and highly politicized - discussion of a topic that is for most women more emotional than medical. Add to that an immediate offensive blitz by some cancer doctors who were concerned that the new guidelines would essentially limit their patients' options for preventing breast-cancer death. "I am appalled and horrified," says Dr. David Dershaw, director of breast imaging at Memorial Sloan-Kettering Cancer Center. "We have something that saves lives, and to say we are not going to do it anymore is unconscionable...
...mammograms may work better in some age groups than in others. What worries experts is that the new guidelines could result in fewer women getting screened overall. Already one-third of American women who should be getting annual mammograms do not get screened. Since 1990, the death rate from breast cancer among women under 50 has been declining, 3% each year, in large part because of the expanded screening guidelines. "[The new recommendations] may erode some of the advances we had made in reducing breast-cancer mortality," says Dr. Therese Bevers, a professor of clinical cancer prevention at M.D. Anderson...