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...Chinese herb Ban Zhi Lian may not be in everyone's lexicon, but to the 80 women with stage IV metastatic breast cancer, who are participating in the second phase of the BZL101 clinical trials, it represents hope and life...
...development company in Emeryville, Calif., that's behind BZL101, there's hope too. The trial is the first FDA-validated clinical study of a potential cancer drug derived from a Chinese medicinal herb, says Dr. Mary Tagliaferri, a co-founder of the company, former practicing acupuncturist and a breast-cancer survivor. "Sixty-two percent of chemotherapy drugs come from natural products, and plants have been the basis of almost every new class of medication," she says. "It makes sense that these plants can act as anticancer agents...
...interest in Ban Zhi Lian, which has traditionally been used to treat swellings, sores and fever, was sparked in 1996 by a fellow acupuncturist, Isaac Cohen, who would later become a co-founder of Bionovo. At that time, Cohen had been treating, for a decade, women who were battling breast cancer with conventional medicines and had run out of treatment options. "In their exhaustion and desperation, they were trying to find an alternative treatment that was not so harsh," says Cohen, who often prescribed herbs to be prepared as teas to ease the side effects of chemo and hormone therapy...
Cohen's early observations about Ban Zhi Lian may have started out as a hunch, but they may hold up. In 1996, Cohen and Tagliaferri, along with Dr. Debu Tripathy, then a breast cancer specialist at the University of California, San Francisco, co-founded the Complementary and Alternative Medicine program at the university's Carol Franc Buck Breast Care Center. Over the next several years, the trio amassed enough evidence about the herb's anticancer properties - in lab tests of animals and breast-cancer cells, BZL101 caused apoptosis or cell death, according to Tagliaferri - to get a green light from...
...hall lifestyle, it only makes sense that we notice the changes in one of the few foods we actively choose for ourselves. It is a sad state when we eagerly anticipate the shift from pumpkin-shaped dyed sugar to reindeer-shaped dyed sugar, but complacently accept eating hangover chicken breast after hangover chicken breast. DICTATED DIETSAlthough Harvard University Dining Services (HUDS) has made a commendable effort to integrate local and seasonal foods into our monotonous diets, the proof is not in the pudding. Our dining halls and their all-inclusive meal plans supposedly exist to foster a culture of learning...