Word: brinkhous
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DIED. KENNETH BRINKHOUS, 92, University of North Carolina medical researcher who developed the first effective treatment for hemophilia; in Chapel Hill, N.C. Brinkhous' early research showed that some hemophiliacs could not produce a bloodclotting protein that was later dubbed Factor VIII. One of his seminal discoveries was a way to use blood plasma to aid in replacing the missing protein...
Grateful Beneficiary. Now solutions are being found for even these problems. The Health Fund of Greater Cleveland has just begun sending around, along with its normal mobile blood-collecting unit, the nation's first auxiliary van equipped with a freeze-centrifuge apparatus. And recently Dr. Kenneth M. Brinkhous, a blood scientist at the University of North Carolina, collaborated with Dr. Edward Shanbrom of the Hyland (Los Angeles) division of Baxter Laboratories to perfect a new AHF six or seven times as strong as Dr. Pool's cryoprecipitate. The new preparation, 30 to 50 times as active as plasma...
...Shanbrom foresees a day when patients will enjoy still greater convenience. Some batches of AHF concentrate have been made 1,000 times more potent than plasma. Eventually, Brinkhous is confident, this will become the standard AHF, so safe and stable that hemophilia victims will be able to carry it around and inject it themselves, into muscle, just as diabetics now do with insulin...
...Direct Measure. "The trouble is," said the University of North Carolina's Dr. Kenneth M. Brinkhous, director of the U.S.'s leading hemophilia research program, "we can only measure the clotting factors indirectly by their effects-usually in the test tube...
...Pathologists Emory Dean Warner, Kenneth Merle Brinkhous, Harry Pratt Smith...
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