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...Canal building requires tricky engineering over obstacles such as hills; the typical solution is a lock, which fills or empties to adjust water height. On Britain's southernmost canal?the 140-km Kennet and Avon, linking the town of Reading on the River Thames to the seaport of Bristol?travelers will encounter dozens of locks, often close together, as in the impressive flight of 16 built in 1810 to climb Caen Hill near Devizes, Wiltshire, pictured above. In traditional canal boats that rent from $1,160 a week, you can chug merrily along, do some lazy fishing and nature watching...

Author: /time Magazine | Title: Canal Plus | 2/23/2004 | See Source »

Kids recite its anchorman quips on blacktops across the country (Booyah! En Fuego!). Athletes clamor for a space in its hilarious SportsCenter ads (in one spot, Mark McGwire, a famous recluse, smashed a computer with a bat at ESPN headquarters in Bristol, Conn.). President Bush is a SportsCenter fan. According to Beta Research, subscribers and cable-system operators rank ESPN as the most valuable network on cable...

Author: /time Magazine | Title: Sports Television: Why ESPN Is The Crown Jewel | 2/23/2004 | See Source »

...countryside alike. Canal building requires tricky engineering over obstacles like hills; the typical solution is a lock, which fills or empties to adjust water height. On Britain's southernmost canal - the 140-km Kennet and Avon, linking the town of Reading on the Thames to the seaport of Bristol - travelers will encounter dozens of locks, often close together, as in the impressive flight of 16 built in 1810 to climb Caen Hill near Devizes, Wiltshire (pictured). In traditional canal boats that rent from $1,160 a week, you can chug merrily along, do some lazy fishing and nature watching, moor...

Author: /time Magazine | Title: Canal Plus | 2/22/2004 | See Source »

Abbott’s actions have angered not just AIDS activists; other big name pharmaceutical companies–like Bristol-Myers Squibb and GlaxoSmithKline–are also livid. These companies produce AIDS drugs that must be combined with Norvir for optimal efficacy, so the Norvir price increase effectively raises the cost of their drugs as well. But Abbott has declined to pass along the Norvir price hike to its own combination drug, Kaletra (which is pre-boosted with Norvir), thereby undercutting its competitors. A savvy business move? Certainly. Kaletra will doubtless gain increased market share as higher Norvir prices...

Author: By Sasha Post, | Title: Drug Bust | 2/19/2004 | See Source »

...medical research ... Of the 21 most important drugs introduced between 1965 and 1992, 15 were developed using knowledge and techniques from federally funded research." A GAO report last year on Taxol, which had worldwide sales of $6.2 billion from 1998 to 2002, noted, "Through a collaboration with NIH, [Bristol-Myers Squibb] benefitted from substantial investments in research conducted or funded by NIH." The collaboration "provided the company with research results that enabled [Taxol] to be quickly commercialized...

Author: /time Magazine | Title: Why Drugs Cost So Much / The Issues '04: Why We Pay So Much for Drugs | 2/2/2004 | See Source »

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