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...separate trial, an experimental drug called rember, developed by a Singapore-based company, also showed some promise in a safety study. Among 321 patients, rember appeared to stall advancement of the disease, degrading the protein tangles that build up in Alzheimer's brains. Potentially, a combination of drug therapies - designed to prevent both plaques and tangles - may prove effective in slowing the progression of the disease...
...dancing fountains in front of the Wynn Macau hotel to the working-class neighborhood of Hac Sa Wan, where you can meet Ng Iat-keong, one of the many poor Macanese for whom the casino boom has been a bust. Ng, 45, is a construction worker who helped build some of Macau's hotel-casinos, including the biggest of them all, Las Vegas Sands' giant Venetian. Yet the money sloshing around in their plush suites hasn't found its way into his pockets. "We are the ones building so many beautiful high rises, but we ourselves don't have...
...Shareholder advocates suggest that the Siemens board may have another motive, too: to build goodwill with the U.S. Securities and Exchange Commission. The SEC is conducting its own investigation into the bribery affair and could slap hefty fines on the company unless Siemens demonstrates that it is taking convincing action to clean up the mess on its own. "The SEC plays a role in this decision in the sense that Siemens wants to show that it is pursuing everyone involved regardless of their past position or reputation," says Daniela Bergdolt of the German Association for the Protection of Securities Ownership...
...doctors - could see permanent solutions next year, though such moves would require a serious look at the tax code and reforming entitlements, both tall orders. "These are big problems. I think these are core policy issues, and having them out there so the public understands and can help build momentum to get these things done is critically important," says Senator Maria Cantwell, a Washington State Democrat. "It helps show the public who's for and against things, so it helps us shape the debate at the presidential level...
Compared with patients who never developed diabetes, patients who had the disease but took insulin along with one additional medication to control blood sugar (typically metformin or glyburide) had 80% fewer brain-clogging amyloid plaques in their brain. Build up of these protein plaques, which are one of the hallmarks of Alzheimer's disease, can interfere with normal communication between nerve cells and cause deficits in memory and cognition. "The group on combination therapy had a very, very low load of neuritic plaques," Beeri says. "Their brains looked almost like normal people." The medications did not, however, do much...