Word: burroughses
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Dates: during 1980-1989
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The results were so remarkable, Windom said, that tests in a dozen medical centers were being halted so that control groups of AIDS sufferers -- who had been receiving only placebos, or dummy drugs -- could immediately begin treatment with AZT. Furthermore, Windom has petitioned the Food and Drug Administration for speedy...
That study, designed by Burroughs Wellcome Co. in collaboration with medical specialists and AIDS experts, began in February and was scheduled to end in December; it involved 282 subjects. Some were victims of AIDS who during the previous four months had also suffered their first bout of PCP. The remaining...
From the start, the company and an independent review board had agreed that if AZT proved to be toxic, the patients would immediately be taken off the drug and the test halted. But if AZT turned out to be clearly beneficial, it would immediately be offered to those patients who...
Scientists at Burroughs Wellcome suspected that the long-unused AZT might be what was needed to stop the AIDS virus. They discovered that when the drug enters a human cell, it is converted by a human enzyme into a "false sugar" ) that resembles, but is not identical to, the sugar...
At the request of Burroughs Wellcome, Samuel Broder and his colleagues at NCI and other institutions tested AZT in late 1984 and early 1985 on AIDS- infected human cells in the test tube and found that it seemed to interfere with viral reproduction. Subsequently, they began testing the drug on...