Word: bypassed
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...Franciscans, whose city council last week proposed the city launch a pot-growing business to provide medicinal marijuana to patients in need. The legal pot conundrum is hardly a new debate in California, but what's notable here is that proponents of the measure have decided to bypass the local representatives by trying to get it on the city ballot in November. That's just what voters need - another referendum passed down by bureaucrats who are too irresolute to do their jobs...
...What seems clear is that Mahathir's resignation is no publicity gambit to shore up support. Even his detractors acknowledge that. "It's definitely not a put-on job or a political gimmick," says oppositionist Lim Kit Siang. (Though Mahathir had multiple-bypass surgery a decade ago, his health is robust for a 76-year-old.) But neither, it seems, does he wish to go because he feels he has accomplished enough and that it's time for younger leaders to take over?as Lee Kuan Yew believed. Mahathir modernized the economy, enabled Malaysia to gain international respect, and gave...
...room only train ticket I could have flown back and forth from New York to Washington not once, but twice, I got a bit peeved. Recently, I was on my way to Wilmington, Delaware to meet my parents. I had painstakingly concocted a route by which I could totally bypass Amtrak: New Jersey Transit to Trenton, then switch to the local SEPTA train, which would take me to Philadelphia and eventually Wilmington - all for the low, low price of $16. For the same ride (minus, of course, the inconvenience of transferring) on Amtrak's unreserved Northeast Direct line...
Wilson's experience isn't all that unusual, and while doctors still aren't exactly sure what's going on, a report in last week's New England Journal of Medicine offers a tantalizing clue. The loss of appetite in bypass patients may be linked to a recently discovered gastric hormone called ghrelin. Not only that, ghrelin may turn out to be one reason we feel hungry in the first place and why it's so hard for dieters to keep weight off. Understanding how ghrelin works could even lead to effective weight-loss drugs or drugs to promote weight...
Cummings is less sure of the third conclusion, that bypass patients have only a quarter as much ghrelin as most people of normal weight. "It was based on only five people," he says, "and it's quite possible that had we studied a sixth, he would not show that." Still, the conclusion makes sense on its face. Ghrelin is produced mostly by cells in the stomach; if large parts of that organ are cut off from the rest of the digestive system, they may well stop churning out the hormone...